Simple Summary Glutathione peroxidase 1 (GPX1), as one of the most important antioxidant
enzymes, maintains cellular redox balance by regulating reactive oxygen species levels. In …

Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …

Abstract Glutathione S‑transferase Pi (GSTP1) is an isozyme encoded by the GST pi gene
that plays an important regulatory role in detoxification, anti‑oxidative damage, and the …

Living organisms use selenium mainly in the form of selenocysteine in the active site of
oxidoreductases. Here, selenium's unique chemistry is believed to modulate the reaction …

Selenium (Se) and manganese (Mn) are essential micronutrients that are important
elements of cell metabolism. They are involved in the composition of enzyme systems and …

Acrylamide (AA) is widely used in soil stabilization, water treatment, and industrial products
and found in certain foods; however, its toxicity is an expanding global concern. Thus, to …

Radiotherapy is applied in about 70% patients with tumors, yet radioresistance of tumor cells
remains a challenge that limits the efficacy of radiotherapy. Ferroptosis, an iron-dependent …

Abstract Background Glutathione S‐transferases (GSTs) polymorphisms may impact on
chronic myeloid leukemia (CML) risk or heterogeneous responses to Imatinib mesylate (IM) …

Glutathione S-transferases are a family of enzymes, whose main role is to detoxify cells from
many exogenous factors, such as xenobiotics or carcinogens. It has also been proven that …

Background: Oxidative stress plays an important role in the pathogenesis of polycystic ovary
syndrome (PCOS). Glutathione peroxidase 1 (GPx1) and catalase (CAT) are the major …