Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …

Atherogenesis, the formation of atherosclerotic plaques, is a complex process that involves
several mechanisms, including endothelial dysfunction, neovascularization, vascular …

Arterial stiffness predicts an increased risk of cardiovascular events. Inflammation plays a
major role in large arteries stiffening, related to atherosclerosis, arteriosclerosis, endothelial …

Atherosclerosis develops preferentially at branches and curvatures of the arterial tree, where
blood flow pattern is disturbed rather than being laminar, and wall shear stress has an …

Expansion on stiff culture substrates activates pro-fibrotic cell programs that are retained by
mechanical memory. Here, we show that priming on physiologically soft silicone substrates …

Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic
kidney diseases. Increased apoptosis, epithelial‐to‐mesenchymal transition, and …