Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …

The lysis of cells in order to extract the nucleic acids or proteins inside it is a crucial unit
operation in biomolecular analysis. This paper presents a critical evaluation of the various …

Tumors are unique and complex ecosystems, in which heterogeneous cell subpopulations
with variable molecular profiles, aggressiveness, and proliferation potential coexist and …

Advances of analytical methods and emerging microfluidic tools have made it possible to
investigate biological processes in living organisms in detail and reach sensitivities sufficient …

Hydrodynamic phenomena are ubiquitous in living organisms and can be used to
manipulate cells or emulate physiological microenvironments experienced in vivo …

A major feature of cancer is the heterogeneity, both intratumoral and intertumoral. Traditional
single-cell techniques have given us a comprehensive understanding of the biological …

Clustered regularly interspaced short palindromic repeats, CRISPR, has recently emerged
as a powerful molecular biosensing tool for nucleic acids and other biomarkers due to its …

Isolated microfluidic stagnation point flows–stagnation point flows formed within microfluidic
interfaces–have come a long way as a tool for characterizing materials …

This article describes the successful use of high surface area cobalt aluminium layered
double hydroxide as an effective electrode material for fabricating highly flexible printed …

Multiplexed RNA in situ hybridization for the analysis of gene expression patterns plays an
important role in investigating development and disease. Here, we present a method for …