Silk fibroin-based biomaterials for cartilage/osteochondral repair

Z Zhou, J Cui, S Wu, Z Geng, J Su - Theranostics, 2022 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not
only causes great physiological and psychological harm to patients, but also puts great …

Silk fibroin as biomaterial for bone tissue engineering

J Melke, S Midha, S Ghosh, K Ito, S Hofmann - Acta biomaterialia, 2016 - Elsevier
Silk fibroin (SF) is a fibrous protein which is produced mainly by silkworms and spiders. Its
unique mechanical properties, tunable biodegradation rate and the ability to support the …

Silk fibroin biomaterials for tissue regenerations

B Kundu, R Rajkhowa, SC Kundu, X Wang - Advanced drug delivery …, 2013 - Elsevier
Regeneration of tissues using cells, scaffolds and appropriate growth factors is a key
approach in the treatments of tissue or organ failure. Silk protein fibroin can be effectively …

Silk-based biomaterials for sustained drug delivery

T Yucel, ML Lovett, DL Kaplan - Journal of Controlled Release, 2014 - Elsevier
Silk presents a rare combination of desirable properties for sustained drug delivery,
including aqueous-based purification and processing options without chemical cross …

Injectable and pH-responsive silk nanofiber hydrogels for sustained anticancer drug delivery

H Wu, S Liu, L **ao, X Dong, Q Lu… - ACS applied materials & …, 2016 - ACS Publications
Silk is useful as a drug carrier due to its biocompatibility, tunable degradation, and
outstanding capacity in maintaining the function of drugs. Injectable silk hydrogels could …

Silk fibroin biomaterials for controlled release drug delivery

EM Pritchard, DL Kaplan - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: Given the benefits of polymer drug delivery implants over traditional periodic
systemic administration, the development of biomaterial systems with the necessary …

The use of silk-based devices for fracture fixation

GS Perrone, GG Leisk, TJ Lo, JE Moreau… - Nature …, 2014 - nature.com
Metallic fixation systems are currently the gold standard for fracture fixation but have
problems including stress shielding, palpability and temperature sensitivity. Recently …

Silk fibroin-based biomaterials for musculoskeletal tissue engineering

D Ma, Y Wang, W Dai - Materials Science and Engineering: C, 2018 - Elsevier
Tissue engineering (TE) is an emerging and promising strategy to heal tissue failure by
integrating science and technology of materials, cells and growth factors. With the increasing …

Strategies for tuning the biodegradation of silk fibroin-based materials for tissue engineering applications

D Umuhoza, F Yang, D Long, Z Hao… - … Science & Engineering, 2020 - ACS Publications
The remarkable features of silk fibroin (SF) from the silkworm (Bombyx mori) have fueled its
application as a candidate biomaterial for tissue regeneration and repair. For an ideal …

[HTML][HTML] Silk structure and degradation

B Liu, Y Song, L **, Z Wang, D Pu, S Lin… - Colloids and Surfaces B …, 2015 - Elsevier
To investigate the structure of silk and its degradation properties, we have monitored the
structure of silk using scanning electron microscopy and frozen sections. Raw silk and …