Recent meta-analyses of structural and functional neuroimaging studies are converging on
a collective core of brain regions affected across most psychiatric disorders, centered on the …

L-DOPA is still the most effective pharmacological therapy for the treatment of motor
symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep …

Commonly used for Parkinson's disease (PD), deep brain stimulation (DBS) produces
marked clinical benefits when optimized. However, assessing the large number of possible …

Depleted of dopamine, the dynamics of the parkinsonian brain impact on both 'action'and
'resting'motor behaviour. Deep brain stimulation has become an established means of …

Affective neuroscience is concerned with identifying the neural bases of emotion. For
historical and methodological reasons, models describing the brain architecture that …

Abnormal phase-amplitude coupling between β and broadband-γ activities has been
identified in recordings from the cortex or scalp of patients with Parkinson's disease. While …

Deep brain stimulation (DBS) for Parkinson's disease is a highly effective treatment in
controlling otherwise debilitating symptoms. Yet the underlying brain mechanisms are …

Deep brain stimulation (DBS) has been reported to be successful in relieving the core motor
symptoms of Parkinson′ s disease (PD) and motor fluctuations in the more advanced …

Subthalamic deep brain stimulation (DBS) is superior to medical therapy for the motor
symptoms of advanced Parkinson's disease (PD), and additional evidence suggests that it …

Applying high-frequency stimulation (HFS) to deep brain structure, known as deep brain
stimulation (DBS), has now been recognized an effective therapeutic option for a wide range …