Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial
extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the …

Gram-negative bacteria shed extracellular outer membrane vesicles (OMVs) during their
normal growth both in vitro and in vivo. OMVs are spherical, bilayered membrane …

Helicobacter pylori is a gastric bacterial pathogen that is etiologically linked to human gastric
cancer. The cytotoxin-associated gene A (CagA) protein of H. pylori, which is delivered into …

Helicobacter pylori is responsible for the most commonly found infection in the world's
population. It is the major risk factor for gastric cancer development. Numerous studies …

Over the past 50 years, steady growth in the field of metalloproteinase biology has shown
that the degradation of extracellular matrix components represents only a fraction of the …

Helicobacter pylori is the leading cause of peptic ulcer disease. The infection has been
implicated in more than 75% of duodenal ulcer cases and 17% of gastric ulcer cases. H …

Colonization of the human stomach with Helicobacter pylori strains containing the cag
pathogenicity island is a risk factor for development of gastric cancer. The cag pathogenicity …

Helicobacter pylori (H. pylori) infection is strongly associated with the development of gastric
diseases but also with several extragastric diseases. The clinical outcomes caused by H …