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Breathing matters
Breathing is a well-described, vital and surprisingly complex behaviour, with behavioural
and physiological outputs that are easy to directly measure. Key neural elements for …
and physiological outputs that are easy to directly measure. Key neural elements for …
[HTML][HTML] Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding
Opioid-induced respiratory depression (OIRD) represents the primary cause of death
associated with therapeutic and recreational opioid use. Within the United States, the rate of …
associated with therapeutic and recreational opioid use. Within the United States, the rate of …
Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm
Inspiratory breathing movements depend on pre-Bötzinger complex (preBötC) interneurons
that express calcium (Ca2+)-activated nonselective cationic current (I CAN) to generate …
that express calcium (Ca2+)-activated nonselective cationic current (I CAN) to generate …
Dbx1 pre-Bötzinger complex interneurons comprise the core inspiratory oscillator for breathing in unanesthetized adult mice
The brainstem pre-Bötzinger complex (preBötC) generates inspiratory breathing rhythms,
but which neurons comprise its rhythmogenic core? Dbx1-derived neurons may play the …
but which neurons comprise its rhythmogenic core? Dbx1-derived neurons may play the …
Microcircuit synchronization and heavy-tailed synaptic weight distribution augment prebötzinger complex bursting dynamics
The preBötzinger Complex (preBötC) encodes inspiratory time as rhythmic bursts of activity
underlying each breath. Spike synchronization throughout a sparsely connected preBötC …
underlying each breath. Spike synchronization throughout a sparsely connected preBötC …
Map** of the excitatory, inhibitory, and modulatory afferent projections to the anatomically defined active expiratory oscillator in adult male rats
V Biancardi, J Saini, A Pageni… - Journal of …, 2021 - Wiley Online Library
The lateral parafacial region (pFL; which encompasses the parafacial respiratory group,
pFRG) is a conditional oscillator that drives active expiration during periods of high …
pFRG) is a conditional oscillator that drives active expiration during periods of high …
Transient suppression of Dbx1 preBötzinger interneurons disrupts breathing in adult mice
NC Vann, FD Pham, JA Hayes, A Kottick… - PLoS …, 2016 - journals.plos.org
Interneurons derived from Dbx1-expressing precursors located in the brainstem
preBötzinger complex (preBötC) putatively form the core oscillator for inspiratory breathing …
preBötzinger complex (preBötC) putatively form the core oscillator for inspiratory breathing …
Forebrain and hindbrain projecting-neurons target the post-inspiratory complex cholinergic neurons
The postinspiratory complex (PiCo) is a region located in the ventromedial medulla involved
with the post-inspiratory activity. PiCo neurons are excitatory (VGlut 2+) and express the …
with the post-inspiratory activity. PiCo neurons are excitatory (VGlut 2+) and express the …
Anatomy of the respiratory neural network
We provide an overview of the neuroanatomy of the respiratory control system including the
circuitry that generates and transmits breathing rhythm; the efferent interneurons that carry …
circuitry that generates and transmits breathing rhythm; the efferent interneurons that carry …
Dbx1 pre-Bötzinger complex interneurons comprise the core inspiratory oscillator for breathing in adult mice
The brainstem pre-Bötzinger complex (preBötC) generates inspiratory breathing rhythms,
but which neurons comprise its rhythmogenic core? Dbx1-derived neurons may play the …
but which neurons comprise its rhythmogenic core? Dbx1-derived neurons may play the …