Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke
Despite many years of research, no biomarkers for stroke are available to use in clinical
practice. Progress in high-throughput technologies has provided new opportunities to …
practice. Progress in high-throughput technologies has provided new opportunities to …
Acute stroke biomarkers: are we there yet?
M Dagonnier, GA Donnan, SM Davis… - Frontiers in …, 2021 - frontiersin.org
Background: Distinguishing between stroke subtypes and knowing the time of stroke onset
are critical in clinical practice. Thrombolysis and thrombectomy are very effective treatments …
are critical in clinical practice. Thrombolysis and thrombectomy are very effective treatments …
Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives
Stroke is one of the leading causes of disability worldwide. Early diagnosis and treatment of
stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke …
stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke …
Blood biomarkers for stroke diagnosis and management
J Kamtchum-Tatuene, GC Jickling - Neuromolecular medicine, 2019 - Springer
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia
Ergothioneine (ET) is a dietary amino-thione with strong antioxidant and cytoprotective
properties and has possible therapeutic potential for neurodegenerative and vascular …
properties and has possible therapeutic potential for neurodegenerative and vascular …
Blood biomarkers to differentiate ischemic and hemorrhagic strokes
A Bustamante, A Penalba, C Orset, L Azurmendi… - Neurology, 2021 - AAN Enterprises
Objective To validate a panel of blood biomarkers to differentiate between ischemic stroke
(IS) and intracerebral hemorrhage (ICH) in patients with suspected stroke. Methods Patients …
(IS) and intracerebral hemorrhage (ICH) in patients with suspected stroke. Methods Patients …
Intracerebral haemorrhage—mechanisms, diagnosis and prospects for treatment and prevention
DJ Seiffge, S Fandler-Höfler, Y Du… - Nature Reviews …, 2024 - nature.com
Intracerebral haemorrhage (ICH) is a devastating condition associated with high mortality
and substantial residual disability among survivors. Effective treatments for the acute stages …
and substantial residual disability among survivors. Effective treatments for the acute stages …
CSF and blood glial fibrillary acidic protein for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
Y Zou, Y Wang, X Ma, D Mu, J Zhong, C Ma… - Ageing Research …, 2024 - Elsevier
Recently included in the 2024 new revised diagnostic criteria of Alzheimer's disease (AD),
glial fibrillary acidic protein (GFAP) has garnered significant attention. A systematic review …
glial fibrillary acidic protein (GFAP) has garnered significant attention. A systematic review …
Ultra-early differential diagnosis of acute cerebral ischemia and hemorrhagic stroke by measuring the prehospital release rate of GFAP
Background Plasma glial fibrillary acidic protein (GFAP) and tau are promising markers for
differentiating acute cerebral ischemia (ACI) and hemorrhagic stroke (HS), but their …
differentiating acute cerebral ischemia (ACI) and hemorrhagic stroke (HS), but their …
Unlocking the potential of stroke blood biomarkers: early diagnosis, ischemic vs. haemorrhagic differentiation and haemorrhagic transformation risk: a comprehensive …
L di Biase, A Bonura, PM Pecoraro… - International Journal of …, 2023 - mdpi.com
Stroke, a complex and heterogeneous disease, is a leading cause of morbidity and mortality
worldwide. The timely therapeutic intervention significantly impacts patient outcomes, but …
worldwide. The timely therapeutic intervention significantly impacts patient outcomes, but …