Going viral: The role of mobile genetic elements in bacterial immunity

B Beamud, F Benz, D Bikard - Cell Host & Microbe, 2024 - cell.com
Bacteriophages and other mobile genetic elements (MGEs) pose a significant threat to
bacteria, subjecting them to constant attacks. In response, bacteria have evolved a …

Prophage mediated control of higher order interactions-insights from multi-level approaches

CC Wendling - Current Opinion in Systems Biology, 2023 - Elsevier
Prophages, latent viral elements residing in bacterial genomes affect bacterial ecology and
evolution in diverse ways. Do these prophage-mediated effects extend beyond the …

Comparative Metagenomic Analysis of Bacteriophages and Prophages in Gnotobiotic Mouse Models

OA Ishola, S Kublik, AC Durai Raj, C Ohnmacht… - Microorganisms, 2024 - mdpi.com
Gnotobiotic murine models are important to understand microbiota–host interactions.
Despite the role of bacteriophages as drivers for microbiome structure and function, there is …

Phage biology: The ins and outs of prophages in bacterial populations

DA Doakes, B Koskella - Current Biology, 2024 - Elsevier
Bacterial genomes often harbor integrated viruses (prophages), which provide novel
functions but also lyse cells under stressful conditions. A new paper combines mathematical …

Evolutionary strategies of Klebsiella phages in a host-diverse environment

C Ferriol-González, P Domingo-Calap - bioRxiv, 2024 - biorxiv.org
Phage-host interactions have been studied using one or a few phages and hosts in simple,
controlled systems. Here, we implemented an experimental design to evolve a 12-phage …

Persistent virulent phages exist in bacterial isolates

PE Dougherty, C Bernard, AB Carstens, K Stanford… - bioRxiv, 2025 - biorxiv.org
Despite the immense diversity of tailed bacteriophages, they are traditionally classified as
either virulent or temperate, with only the latter thought capable of long-term persistence in …

[HTML][HTML] Pijolavirus UFJF_PfSW6 Infection in Pseudomonas fluorescens Induces a Prophage Belonging to a Novel Genus in Peduoviridae Family

PMP Vidigal, JM Brum, MES Lopez, HC Mantovani… - DNA, 2024 - mdpi.com
Background/Objectives: This study explores the genome sequencing data from the infection
of Pseudomonas fluorescens UFV 041 by the bacteriophage Pijolavirus UFJF_PfSW6 …

Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence

A Korša, M Baur, NKE Schulz, JM Anaya-Rojas… - bioRxiv, 2024 - biorxiv.org
Understanding the drivers and mechanisms of virulence evolution is still a major goal of
evolutionary biologists and epidemiologists. Theory predicts that the way virulence evolves …