It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …

The emerging trends in the combinatorial chemistry and drug design have led to the
development of drug candidates with greater lipophilicity, high molecular weight and poor …

Carvedilol (CRV) is an antihypertensive drug with both alpha and beta receptor blocking
activity used to preclude angina and cardiac arrhythmias. To overcome the low, variable oral …

Oral administration of medication is the first option when patient compliance is considered.
However, many barriers face oral absorption of drugs that limit bioavailability in about 90 …

Liposomes are lipid based vesicular systems that offer novel platform for versatile drug
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …

The aim of this study was to develop different vesicular systems for sertaconazole nitrate and
evaluate the ability of targeting deep skin layers to treat dermal fungal infection. Therefore …

Numerous disorders go untreated owing to a lack of a suitable drug delivery technology or
an appropriate therapeutic moiety, particularly when toxicities and side effects are a major …

The diversity of lipid excipients available commercially has enabled versatile formulation
design of lipid-based drug delivery systems for enhancing the oral absorption of poorly …

The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Vesicular drug delivery systems have gained wide attention in the field of nanotechnology.
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …