Intestinal adaptive immune responses influence host health, yet only a few intestinal
bacteria species that induce cognate adaptive immune responses during homeostasis have …

Cardioimmunology is a field that encompasses the immune cells and pathways that
modulate cardiac function in homeostasis and regulate the temporal balance between tissue …

Both microbial and host genetic factors contribute to the pathogenesis of autoimmune
diseases,,,. There is accumulating evidence that microbial species that potentiate chronic …

Abstract T-helper-17 (TH17) cells have critical roles in mucosal defence and in autoimmune
disease pathogenesis,,. They are most abundant in the small intestine lamina propria, where …

Visceral adipose tissue (VAT) hosts a population of regulatory T (Treg) cells, with a unique
phenotype, that controls local and systemic inflammation and metabolism. Generation of a T …

We describe the generation of ovalbumin (OVA)‐specific, MHC class II‐restricted αβ T cell
receptor (TCR) transgenic mice. Initial attempts at generating these transgenic mice utilized …

Despite accumulating evidence that regulatory T cells play a crucial role in preventing
autoimmunity, the processes underlying their generation during immune repertoire formation …

The action of tissue Transglutaminase1 (TGase) on specific protein-bound glutamine
residues plays a critical role in numerous biological processes2–5. Here we provide …

Multiple sclerosis (MS) is considered to be an autoimmune disease of the central nervous
system (CNS) that in many patients first presents clinically as optic neuritis. The relationship …

Many tumor-associated antigens are derived from nonmutated “self” proteins. T cells
infiltrating tumor deposits recognize self-antigens presented by tumor cells and can be …