Novel antimicrobial agents for combating antibiotic-resistant bacteria
Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …
the number of papers reporting its use, which increases exponentially since the early 2010s …
Galleria mellonella as an infection model: an in-depth look at why it works and practical considerations for successful application
The larva of the greater wax moth Galleria mellonella is an increasingly popular model for
assessing the virulence of bacterial pathogens and the effectiveness of antimicrobial agents …
assessing the virulence of bacterial pathogens and the effectiveness of antimicrobial agents …
Phage resistance formation and fitness costs of hypervirulent Klebsiella pneumoniae mediated by K2 capsule-specific phage and the corresponding mechanisms
M Tang, Z Huang, X Zhang, J Kong, B Zhou… - Frontiers in …, 2023 - frontiersin.org
Introduction Phage is promising for the treatment of hypervirulent Klebsiella pneumoniae
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …
(hvKP) infections. Although phage resistance seems inevitable, we found that there still was …
[HTML][HTML] Advances in bacteriophage therapy against relevant multidrug-resistant pathogens
The increase of multiresistance in bacteria and the shortage of new antibiotics in the market
is becoming a major public health concern. The World Health Organization (WHO) has …
is becoming a major public health concern. The World Health Organization (WHO) has …
Biological challenges of phage therapy and proposed solutions: a literature review
Introduction: In light of the emergence of antibiotic-resistant bacteria, phage (bacteriophage)
therapy has been recognized as a potential alternative or addition to antibiotics in Western …
therapy has been recognized as a potential alternative or addition to antibiotics in Western …
Phage therapy: An alternative treatment modality for MDR bacterial infections
The increasing global incidence of multidrug-resistant (MDR) bacterial infections threatens
public health and compromises various aspects of modern medicine. Recognising the …
public health and compromises various aspects of modern medicine. Recognising the …
Identification of three capsule depolymerases in a bacteriophage infecting Klebsiella pneumoniae capsular types K7, K20, and K27 and therapeutic application
Background Klebsiella pneumoniae capsular types K1, K2, K5, K20, K54, and K57 are
prevalent hypervirulent types associated with community infections, and worrisomely …
prevalent hypervirulent types associated with community infections, and worrisomely …
Novel Klebsiella pneumoniae K23-Specific Bacteriophages From Different Families: Similarity of Depolymerases and Their Therapeutic Potential
Antibiotic resistance is a major public health concern in many countries worldwide. The
rapid spread of multidrug-resistant (MDR) bacteria is the main driving force for the …
rapid spread of multidrug-resistant (MDR) bacteria is the main driving force for the …
[HTML][HTML] In vitro and in vivo assessment of phage therapy against Staphylococcus aureus causing bovine mastitis
C Ngassam-Tchamba, JN Duprez, M Fergestad… - Journal of global …, 2020 - Elsevier
Objective The aim of this study was to assess the efficacy of lytic bacteriophages on
Staphylococcus aureus causing bovine mastitis, by in vitro and in vivo assays using Galleria …
Staphylococcus aureus causing bovine mastitis, by in vitro and in vivo assays using Galleria …