Host directed therapy against infection by boosting innate immunity

P Bergman, R Raqib, RS Rekha, B Agerberth… - Frontiers in …, 2020 - frontiersin.org
The innate immune system constitutes the first line of defense against invading pathogens,
regulating the normal microbiota and contributes to homeostasis. Today we have obtained …

Treatment of bacterial infections with β-lactams: cooperation with innate immunity

M Mondemé, C Carnoy, JC Sirard… - Infection and …, 2023 - journals.asm.org
ABSTRACT β-Lactams are the most widely prescribed antibiotics used for the control and
treatment of bacterial infections. The direct effect of β-lactams on bacteria is well studied …

Study on antibiotic susceptibility of Salmonella typhimurium L forms to the third and forth generation cephalosporins

C Yang, H Li, T Zhang, Y Chu, J Zuo, D Chen - Scientific reports, 2020 - nature.com
Salmonella typhimurium is a pathogenic gram-negative bacterium, which is found primarily
in the intestinal lumen. It often causes diarrhea in infants and young children and leads to …

Early life administration of Bifidobacterium bifidum BD-1 alleviates long-term colitis by remodeling the gut microbiota and promoting intestinal barrier development

C Peng, J Li, Z Miao, Y Wang, S Wu, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic intestinal disease characterized by microbiota
disturbance and intestinal mucosal damage. The current study aimed to investigate the …

Effect of Nigella sativa oil and ciprofloxacin against bacterial infection on gene expression in Nile tilapia (Oreochromis niloticus) blood

AM Hal, I Manal - Aquaculture, 2021 - Elsevier
The effect of both Nigella sativa oil (NSO) and ciprofloxacin (Cip) was investigated by
evaluating their therapeutic and immunity properties on serum biochemical parameters, and …

Ciprofloxacin promotes polarization of CD86+CD206 macrophages to suppress liver cancer

M Fan, S Chen, Y Weng, X Li, Y Jiang… - Oncology …, 2020 - spandidos-publications.com
Gut microbiota can promote tumor development by producing toxic metabolites and
inhibiting the function of immune cells. Previous studies have demonstrated that gut …

Inhibitory concentrations of ciprofloxacin induce an adaptive response promoting the intracellular survival of Salmonella enterica Serovar Typhimurium

S Sridhar, S Forrest, D Pickard, C Cormie, EA Lees… - Mbio, 2021 - journals.asm.org
Antimicrobial resistance (AMR) is a pressing global health crisis, which has been fueled by
the sustained use of certain classes of antimicrobials, including fluoroquinolones. While the …

Study the Ability of Salmonella typhimiurm to Induce Cytokine TNFα in Mice Treated with Olive Leaves Extract and Ciprofloxacin

DHD Al Mnshad, AT Al Joudi, LQ Jawad… - Archives of Razi …, 2022 - pmc.ncbi.nlm.nih.gov
TNF-α is a type of cytokine that is produced by inflammatory cells. These inflammatory cells
produce cytokines such as TNF-α, IFN-γ, IL-1, etc. Ciprofloxacin is the last drug of choice to …

Therapeutic effect of Nigella sativa oil and ciprofloxacin against bacterial infection based on interleukin 1β expression and kidney histopathological alterations in …

AM Hal, MI El‐Barbary - Aquaculture Research, 2021 - Wiley Online Library
The study evaluated the effect of Nigella sativa oil (NSO) and ciprofloxacin (CFX) on
Oreochromis niloticus infected with Aeromonas hydrophila and Pseudomonas fluorescens …