Coffee is one of the most widely consumed beverages, which has several effects on the
human body. In particular, current evidence suggests that coffee consumption is associated …

Background: Ageing can be simply defined as the process of becoming older, which is
genetically determined but also environmentally modulated. With the continuous increase of …

Methamphetamine (Meth) is a powerful illicit psychostimulant, widely used for recreational
purposes. Besides disrupting the monoaminergic system and promoting oxidative brain …

Microglia are the largest myeloid cell population in the brain. During injury, disease, or
inflammation, microglia adopt different functional states primarily involved in restoring brain …

c‐Src was the first protein kinase to be described as capable of phosphorylating tyrosine
residues. Subsequent identification of other tyrosine‐phosphorylating protein kinases with a …

Background Intracerebral hemorrhage (ICH) is one of the stroke subtypes with the highest
mortality. Secondary brain injury is associated with neurological dysfunction and poor …

Alcohol abuse adversely affects the lives of millions of people worldwide. Deficits in synaptic
transmission and in microglial function are commonly found in human alcohol abusers and …

Chlorogenic acid (CGA) is a phenolic compound that is widely distributed in honeysuckle,
Eucommia, fruits and vegetables. It has various biological functions, including …

The importance of diet in preventing non-communicable diseases is well established, with
polyphenol consumption suggested to impact cardiovascular disease development …

The increased healthspan afforded by coffee intake provides novel opportunities to identify
new therapeutic strategies. Caffeine has been proposed to afford benefits through …