Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

[HTML][HTML] Arsenic: a review on a great health issue worldwide

G Genchi, G Lauria, A Catalano, A Carocci… - Applied Sciences, 2022 - mdpi.com
Arsenic intoxication represents a worldwide health problem and occurs mainly through
drinking water. Arsenic, a metalloid and naturally occurring element, is one of the most …

Mechanistic understanding of the toxic effects of arsenic and warfare arsenicals on human health and environment

S Muzaffar, J Khan, R Srivastava, MS Gorbatyuk… - Cell Biology and …, 2023 - Springer
Worldwide, more than 200 million people are estimated to be exposed to unsafe levels of
arsenic. Chronic exposure to unsafe levels of groundwater arsenic is responsible for …

Environmental factors in cardiovascular disease

KE Cosselman, A Navas-Acien… - Nature Reviews …, 2015 - nature.com
Environmental exposure is an important but underappreciated risk factor contributing to the
development and severity of cardiovascular disease (CVD). The heart and vascular system …

The effects of arsenic exposure on neurological and cognitive dysfunction in human and rodent studies: a review

CR Tyler, AM Allan - Current environmental health reports, 2014 - Springer
Arsenic toxicity is a worldwide health concern as several millions of people are exposed to
this toxicant via drinking water, and exposure affects almost every organ system in the body …

Small-magnitude effect sizes in epigenetic end points are important in children's environmental health studies: the children's environmental health and disease …

CV Breton, CJ Marsit, E Faustman… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Neurotoxic effects of heavy metal pollutants in the environment: Focusing on epigenetic mechanisms

G Yu, L Wu, Q Su, X Ji, J Zhou, S Wu, Y Tang… - Environmental Pollution, 2024 - Elsevier
The pollution of heavy metals (HMs) in the environment is a significant global environmental
issue, characterized by its extensive distribution, severe contamination, and profound …

DNA methylation of cord blood cell types: applications for mixed cell birth studies

KM Bakulski, JI Feinberg, SV Andrews, J Yang… - Epigenetics, 2016 - Taylor & Francis
Epigenome-wide association studies of disease widely use DNA methylation measured in
blood as a surrogate tissue. Cell proportions can vary between people and confound …

Update of the risk assessment of inorganic arsenic in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2024 - Wiley Online Library
Abstract The European Commission asked EFSA to update its 2009 risk assessment on
arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the …

Arsenic and environmental health: state of the science and future research opportunities

DJ Carlin, MF Naujokas, KD Bradham… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: Exposure to inorganic and organic arsenic compounds is a major public health
problem that affects hundreds of millions of people worldwide. Exposure to arsenic is …