TUNEL assay: a powerful tool for kidney injury evaluation

CL Moore, AV Savenka, AG Basnakian - International journal of molecular …, 2021 - mdpi.com
Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay is a long-
established assay used to detect cell death-associated DNA fragmentation (3'-OH DNA …

Brain-derived neurotrophic factor (BDNF): a multifaceted marker in chronic kidney disease

B Afsar, RE Afsar - Clinical and Experimental Nephrology, 2022 - Springer
Despite advances in diagnostic tools and therapeutic options, chronic kidney disease (CKD)
is still a global health problem associated with increased morbidity and mortality. Insulin …

7, 8-Dihydroxyflavone alleviates Endoplasmic Reticulum Stress in cafeteria diet-induced metabolic syndrome

E Sahin, N Saglam, S Erdem, E Alvuroglu, I Abidin… - Life Sciences, 2022 - Elsevier
Abstract Aims Prolonged Endoplasmic Reticulum Stress (ERS) is involved in the
pathogenesis of metabolic syndrome, including type-2 diabetes mellitus, cardiovascular …

Protective effect of royal jelly on fluoride-induced nephrotoxicity in rats via the some protein biomarkers signalling pathways: a new approach for kidney damage

A Aslan, S Beyaz, O Gok, MI Can, G Parlak… - Biomarkers, 2022 - Taylor & Francis
Introduction Protective effect of royal jelly (RJ) on fluoride-induced nephrotoxicity was
investigated in this study. Methods 42 healthy male Wistar rats (n= 42, 8 weeks of age) were …

Zeaxanthin Attenuates the Vicious Circle Between Endoplasmic Reticulum Stress and Tau Phosphorylation: Involvement of GSK-3β Activation

LN Zhang, MJ Li, YH Shang, YR Liu… - Journal of …, 2022 - content.iospress.com
Background: Alzheimer's disease (AD) characterized by neurofibrillary tangles caused by
hyperphosphorylated tau is the most common cause of dementia. Zeaxanthin (Zea), derived …

Brain-derived neurotrophic factor reduces long-term mortality in patients with coronary artery disease and chronic kidney disease

CY Hsu, WHH Sheu, IT Lee - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Objectives Chronic kidney disease (CKD) is a risk factor for coronary artery disease (CAD).
We examined the effects of circulating brain-derived neurotrophic factor (BDNF) on long …

The role of the unfolded protein response on renal lipogenesis in C57BL/6 mice

E Figueroa-Juárez, LG Noriega, C Pérez-Monter… - Biomolecules, 2021 - mdpi.com
Renal injury observed in several pathologies has been associated with lipid accumulation in
the kidney. While it has been suggested that the accumulation of renal lipids depends on …

Brain-derived neurotrophic factor associated with kidney function

CY Hsu, WHH Sheu, IT Lee - Diabetology & Metabolic Syndrome, 2023 - Springer
Background We examined the relationship between brain-derived neurotrophic factor
(BDNF) and chronic kidney disease (CKD). Methods First, a cross-sectional study was …

Investigation of the Effects of Formaldehyde Exposure on BDNF and FGF23 Levels in Kidney Tissues of Rats

F Aksu, RF Akkoç, A Kavaklı - Kafkas Journal of Medical Sciences - dergipark.org.tr
Aim: Formaldehyde (FA) is a highly toxic chemical agent that can easily turn into gas at room
temperature. It has a wide range of uses. Anatomists, pathologists, and histologists are …

Caracterização da resposta inflamatória e do eixo endócrino ósteo-muscular e influências genéticas associadas durante uma prova extenuante de longa duração de …

MECM Fontes - 2021 - search.proquest.com
As provas extenuantes de longa duração ultrapassam os limites normais de intensidade e
esforço, sendo os metabolismos ósseo e muscular fundamentais, tanto a nível mecânico …