Thalamoreticular circuitry plays a key role in arousal, attention, cognition, and sleep
spindles, and is linked to several brain disorders. A detailed computational model of mouse …

Predictive processing theories conceptualize neocortical feedback as conveying
expectations and contextual attention signals derived from internal cortical models, playing …

The successful pursuit of goals requires the coordinated execution and termination of
actions that lead to positive outcomes. This process relies on motivational states that are …

The medial prefrontal cortex (mPFC) has long been recognized as the key component of the
neurocircuitry involved in various social as well as non-social behaviors, however, little is …

Sleep spindles are associated with the beginning of deep sleep and memory consolidation
and are disrupted in schizophrenia and autism. In primates, distinct core and matrix …

The thalamic reticular nucleus (TRN), receiving excitatory inputs from thalamic nuclei and
cortical areas, regulates thalamic sensory processing through its inhibitory projections to …

Thalamoreticular circuitry is known to play a key role in attention, cognition and the
generation of sleep spindles, and is implicated in numerous brain disorders, but the cellular …

The thalamus is a key element of sensory transmission in the brain, as it gates and selects
sensory streams through a modulation of its internal activity. A preponderant role in these …

Sensory perception requires a set of complex feedforward and feedback processes between
the periphery, subcortical pathways, and the sensory cortices. For most sensory systems …

In this issue, Wang and colleagues solve an important puzzle in the understanding of
schizophrenia. Previous work has linked N-methyl-D-aspartate (NMDA) receptor …