The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …

Lipid nanoparticles (LNPs) are currently the most promising clinical nucleic acids drug
delivery vehicles. LNPs prevent the degradation of cargo nucleic acids during blood …

Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …

In the advancement of tumor therapy, in addition to the search for new antitumor
compounds, the development of nano-drug delivery systems has opened up new pathways …

Abstract mRNA therapeutics have emerged as powerful tools for cancer immunotherapy in
accordance with their superiority in expressing all sequence‐known proteins in vivo. In …

Nucleic acid (NA)-based biopharmaceuticals have emerged as promising therapeutic
modalities. NA therapeutics are a diverse class of RNA and DNA and include antisense …

To improve liposomes' usage as drug delivery vehicles, cryoprotectants can be utilized to
prevent constituent leakage and liposome instability. Cryoprotective agents (CPAs) or …

As an interesting cancer immunotherapy approach, cancer vaccines have been developed
to deliver tumor antigens and adjuvants to antigen-presenting cells (APCs). Although the …

From the early days of research on RNA biology and biochemistry, there was an interest to
utilize this knowledge and RNA itself for therapeutic applications. Today, we have a series of …

Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current treatments available for variety of cancers is considered to be suboptimal …