Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W **ao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics

O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
Pseudomonas aeruginosa is one of the six bacterial pathogens, Enterococcus faecium,
Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas …

[HTML][HTML] Biofilms by bacterial human pathogens: Clinical relevance-development, composition and regulation-therapeutical strategies

A Schulze, F Mitterer, JP Pombo, S Schild - Microbial Cell, 2021 - ncbi.nlm.nih.gov
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

Genomic and Metabolic Characteristics of the Pathogenicity in Pseudomonas aeruginosa

T De Sousa, M Hébraud, MLNE Dapkevicius… - International journal of …, 2021 - mdpi.com
In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance

JMA Blair, GE Richmond, LJV Piddock - Future microbiology, 2014 - Taylor & Francis
Gram-negative bacteria express a plethora of efflux pumps that are capable of transporting
structurally varied molecules, including antibiotics, out of the bacterial cell. This efflux lowers …

The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms

T Rasamiravaka, Q Labtani, P Duez… - BioMed research …, 2015 - Wiley Online Library
P. aeruginosa is an opportunistic pathogenic bacterium responsible for both acute and
chronic infections. Beyond its natural resistance to many drugs, its ability to form biofilm, a …

Ethylene signaling in rice and Arabidopsis: New regulators and mechanisms

H Zhao, CC Yin, B Ma, SY Chen… - Journal of Integrative …, 2021 - Wiley Online Library
Ethylene is a gaseous hormone which plays important roles in both plant growth and
development and stress responses. Based on studies in the dicot model plant species …

The multiple signaling systems regulating virulence in Pseudomonas aeruginosa

P Nadal Jimenez, G Koch, JA Thompson… - Microbiology and …, 2012 - Am Soc Microbiol
Cell-to-cell communication is a major process that allows bacteria to sense and coordinately
react to the fluctuating conditions of the surrounding environment. In several pathogens, this …

Evolution of two-component signal transduction systems

EJ Capra, MT Laub - Annual review of microbiology, 2012 - annualreviews.org
To exist in a wide range of environmental niches, bacteria must sense and respond to a
variety of external signals. A primary means by which this occurs is through two-component …

Biofilm Matrix and Its Regulation in Pseudomonas aeruginosa

Q Wei, LZ Ma - International journal of molecular sciences, 2013 - mdpi.com
Biofilms are communities of microorganisms embedded in extracellular polymeric
substances (EPS) matrix. Bacteria in biofilms demonstrate distinct features from their free …