Systemic lupus erythematosus (SLE) is an autoimmune disease that has diverse clinical
manifestations, ranging from restricted cutaneous involvement to life-threatening systemic …

The Mediterranean diet is considered as the foremost dietary regimen and its adoption is
associated with the prevention of degenerative diseases and an extended longevity. The …

Aim Imbalance of T-helper-cell (TH) subsets (TH1/TH2/TH17) and regulatory T-cells (Tregs)
is suggested to contribute to the pathogenesis of Systemic lupus erythematosus (SLE) …

Systemic lupus erythematosus (SLE) is a complex clinical syndrome, elements of which
remain poorly understood. Although recognized over 140 years ago when Kaposi recorded …

Systemic lupus erythematosus (SLE) is a severe chronic systemic autoimmune disease
caused by complicated interactions among genetic, epigenetic, and immunological factors …

Objective To assess the safety of interleukin‐6 receptor inhibition and to collect preliminary
data on the clinical and immunologic efficacy of tocilizumab in patients with systemic lupus …

Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

CD4+ follicular regulatory T (Tfr) cells suppress B cell responses through modulation of
follicular helper T (Tfh) cells and germinal center (GC) development. We found that Tfr cells …

Depression and anxiety cause severe loss of quality of life for patients with systemic lupus
erythematosus. The causes and factors that contribute to these psychological manifestations …

Cytokines play an important role in host defense against microorganisms. They orchestrate
innate immunity by inducing protective local inflammation and systemic acute phase …