Vascular contributions to Alzheimer's disease
LB Eisenmenger, A Peret, BM Famakin, A Spahic… - Translational …, 2023 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …
Astrocyte reactivity and reactive astrogliosis: costs and benefits
Astrocytes are the most abundant cells in the central nervous system (CNS) that provide
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke
Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …
essential roles in maintaining normal brain function, as they are a critical structural and …
Cerebral blood flow and autoregulation: current measurement techniques and prospects for noninvasive optical methods
Cerebral blood flow (CBF) and cerebral autoregulation (CA) are critically important to
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …
The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common cause of dementia. Deposition of amyloid‐β (Aβ) remains a hallmark feature of the …
common cause of dementia. Deposition of amyloid‐β (Aβ) remains a hallmark feature of the …
The glia/neuron ratio: how it varies uniformly across brain structures and species and what that means for brain physiology and evolution
S Herculano‐Houzel - Glia, 2014 - Wiley Online Library
It is a widespread notion that the proportion of glial to neuronal cells in the brain increases
with brain size, to the point that glial cells represent “about 90% of all cells in the human …
with brain size, to the point that glial cells represent “about 90% of all cells in the human …
Brain arteriolosclerosis
Abstract Brain arteriolosclerosis (B-ASC), characterized by pathologic arteriolar wall
thickening, is a common finding at autopsy in aged persons and is associated with cognitive …
thickening, is a common finding at autopsy in aged persons and is associated with cognitive …
The contribution of astrocytes to the neuroinflammatory response in multiple sclerosis and experimental autoimmune encephalomyelitis
R Brambilla - Acta neuropathologica, 2019 - Springer
Neuroinflammation is the coordinated response of the central nervous system (CNS) to
threats to its integrity posed by a variety of conditions, including autoimmunity, pathogens …
threats to its integrity posed by a variety of conditions, including autoimmunity, pathogens …
Astrocytes: biology and pathology
Astrocytes are specialized glial cells that outnumber neurons by over fivefold. They
contiguously tile the entire central nervous system (CNS) and exert many essential complex …
contiguously tile the entire central nervous system (CNS) and exert many essential complex …
Toll‐like receptor 4 is required for α‐synuclein dependent activation of microglia and astroglia
Alpha‐synucleinopathies (ASP) are neurodegenerative disorders, characterized by
accumulation of misfolded α‐synuclein, selective neuronal loss, and extensive gliosis. It is …
accumulation of misfolded α‐synuclein, selective neuronal loss, and extensive gliosis. It is …