Multiple endocrine neoplasia type 1: latest insights

ML Brandi, SK Agarwal, ND Perrier, KE Lines… - Endocrine …, 2021 - academic.oup.com
Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an
autosomal dominant pattern, is continuing to raise great interest for endocrinology …

Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets

CK Maharjan, PH Ear, CG Tran, JR Howe… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

Pancreatic neuroendocrine neoplasms in multiple endocrine neoplasia type 1

F Marini, F Giusti, F Tonelli, ML Brandi - International Journal of Molecular …, 2021 - mdpi.com
Pancreatic neuroendocrine tumors (pNETs) are a rare group of cancers accounting for about
1–2% of all pancreatic neoplasms. About 10% of pNETs arise within endocrine tumor …

Management recommendations for pancreatic manifestations of von Hippel–Lindau disease

S Laks, R van Leeuwaarde, D Patel, XM Keutgen… - Cancer, 2022 - Wiley Online Library
Von Hippel–Lindau disease (VHL) is a multineoplasm inherited disease manifesting with
hemangioblastoma of the central nervous system and retina, adrenal pheochromocytoma …

DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association

V Lakis, RT Lawlor, F Newell, AM Patch… - Communications …, 2021 - nature.com
Here we report the DNA methylation profile of 84 sporadic pancreatic neuroendocrine
tumors (PanNETs) with associated clinical and genomic information. We identified three …

The chromatin remodeler ATRX: role and mechanism in biology and cancer

Y Pang, X Chen, T Ji, M Cheng, R Wang, C Zhang… - Cancers, 2023 - mdpi.com
Simple Summary ATRX is one of the most frequently mutated tumor suppressor genes in
human cancers. ATRX protein is a chromatin remodeler and transcriptional regulator that is …

Clinical epigenetics of neuroendocrine tumors: the road ahead

A Colao, F De Nigris, R Modica, C Napoli - Frontiers in Endocrinology, 2020 - frontiersin.org
Neuroendocrine tumors, or NETs, are cancer originating in neuroendocrine cells. They are
mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by …

Prognostic factors for the outcome of nonfunctioning pancreatic neuroendocrine tumors in MEN1: a systematic review of literature

SM Sadowski, CRC Pieterman… - Endocrine-related …, 2020 - erc.bioscientifica.com
Metastatic duodenopancreatic neuro-endocrine tumors (dpNETs) are the most important
disease-related cause of death in patients with multiple endocrine neoplasia type 1 (MEN1) …

[HTML][HTML] Liquid biopsy and preclinical tools for advancing diagnosis and treatment of patients with pancreatic neuroendocrine neoplasms

B Smolkova, A Kataki, J Earl, I Ruz-Caracuel… - Critical Reviews in …, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are rare cancers with broad challenges for
their management. The main clinical obstacles are the high rate of patients diagnosed at …

RNA binding motif 47 (RBM47): emerging roles in vertebrate development, RNA editing and cancer

PKM Shivalingappa, V Sharma, A Shiras… - Molecular and Cellular …, 2021 - Springer
RNA-binding proteins (RBPs) are critical players in the post-transcriptional regulation of
gene expression and are associated with each event in RNA metabolism. The term 'RNA …