Retinal development and maturation are orchestrated by a series of interacting signalling
networks that drive the morphogenetic transformation of the anterior develo** brain …

The evolution of pluripotent stem cell-derived retinal organoids (ROs) has brought
remarkable opportunities for developmental studies while also presenting new therapeutic …

Retinal organoids (ROs), which are derived from stem cells, can automatically form three-
dimensional laminar structures that include all cell types and the ultrastructure of the retina …

Stem cell scientists have developed methods for the self-formation of artificial organs, often
referred to as organoids. Organoids can be used as model systems for research in multiple …

Peptide-based hydrogels have great potential for applications in tissue engineering, drug
delivery, and so on. We systematically synthesize, characterize, and investigate the self …

The stem cell-based retinal ganglion cells (RGCs) replacement therapy offers a potential to
restore vision in progressive optic neuropathies including glaucoma by replacing …

Recent research effort in biomaterial development has largely focused on engineering bio-
instructive materials to stimulate specific cell signaling. Assessing the biological …

Poly (γ-benzyl-L-glutamate)(PBG) made biomimetic scaffolds are explored as candidate
materials for corneal nerve regeneration and neurotrophic keratopathy treatment. The PBG …

Nanofibers fabrication nowadays has become unimaginable without mentioning or research
involving the technique of electrospinning. Due to the vast possibilities that this technique …

Background To culture human induced pluripotent stem cells (hiPSCs)-derived retinal
ganglion cells (RGCs) with appropriate structure and functionality is critical for cell therapy of …