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[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …
Pulmonary complications of mechanical ventilation in neonates
Mechanical ventilation is necessary and life saving in many neonates. Most complications
are inherent to this intervention and cannot be confused with iatrogenic errors in judgment or …
are inherent to this intervention and cannot be confused with iatrogenic errors in judgment or …
[HTML][HTML] Role of lipid ordered/disordered phase coexistence in pulmonary surfactant function
C Casals, O Cañadas - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
The respiratory epithelium has evolved to produce a complicated network of extracellular
membranes that are essential for breathing and, ultimately, survival. Surfactant membranes …
membranes that are essential for breathing and, ultimately, survival. Surfactant membranes …
Positive pressure ventilation: what is the real cost?
N Soni, P Williams - British journal of anaesthesia, 2008 - academic.oup.com
Positive pressure ventilation is a radical departure from the physiology of breathing
spontaneously. The immediate physiological consequences of positive pressure ventilation …
spontaneously. The immediate physiological consequences of positive pressure ventilation …
Pulmonary surfactant function is abolished by an elevated proportion of cholesterol
L Gunasekara, S Schürch, WM Schoel, K Nag… - … et Biophysica Acta (BBA …, 2005 - Elsevier
A molecular film of pulmonary surfactant strongly reduces the surface tension of the lung
epithelium–air interface. Human pulmonary surfactant contains 5–10% cholesterol by mass …
epithelium–air interface. Human pulmonary surfactant contains 5–10% cholesterol by mass …
Benzalkonium chloride and cetylpyridinium chloride induce apoptosis in human lung epithelial cells and alter surface activity of pulmonary surfactant monolayers
S Kanno, S Hirano, H Kato, M Fukuta, T Mukai… - Chemico-Biological …, 2020 - Elsevier
Quaternary ammonium compounds (eg, benzalkonium chloride (BAC) and cetylpyridinium
chloride (CPC)) constitute a group of cationic surfactants are widely used for personal …
chloride (CPC)) constitute a group of cationic surfactants are widely used for personal …
Effect of cholesterol on the biophysical and physiological properties of a clinical pulmonary surfactant
E Keating, L Rahman, J Francis, A Petersen… - Biophysical journal, 2007 - cell.com
Pulmonary surfactant is a complex mixture of lipids and proteins that forms a surface-active
film at the air-water interface of alveoli capable of reducing surface tension to near 0mN/m …
film at the air-water interface of alveoli capable of reducing surface tension to near 0mN/m …
An elevated level of cholesterol impairs self-assembly of pulmonary surfactant into a functional film
In adult respiratory distress syndrome, the primary function of pulmonary surfactant to
strongly reduce the surface tension of the air-alveolar interface is impaired, resulting in …
strongly reduce the surface tension of the air-alveolar interface is impaired, resulting in …
The molecular mechanism of monolayer-bilayer transformations of lung surfactant from molecular dynamics simulations
The aqueous lining of the lung surface exposed to the air is covered by lung surfactant, a
film consisting of lipid and protein components. The main function of lung surfactant is to …
film consisting of lipid and protein components. The main function of lung surfactant is to …
1, 2-Dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) monolayers: influence of temperature, pH, ionic strength and binding of alkaline earth cations
P Garidel, A Blume - Chemistry and physics of lipids, 2005 - Elsevier
Ion binding and lipid ionization of the acidic phospholipid 1, 2-dimyristoyl-sn-glycero-3-
phosphoglycerol (DMPG) in monolayers was studied by measuring the lateral pressure Π as …
phosphoglycerol (DMPG) in monolayers was studied by measuring the lateral pressure Π as …