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Health risks associated with the pharmaceuticals in wastewater
The overwhelming population growth in recent decades and water crisis along with limited
and uneven geographical distribution of fresh water resources is a growing challenge for the …
and uneven geographical distribution of fresh water resources is a growing challenge for the …
Bioanalysis in drug discovery and development
Recent years have witnessed the introduction of several high-quality review articles into the
literature covering various scientific and technical aspects of bioanalysis. Now it is widely …
literature covering various scientific and technical aspects of bioanalysis. Now it is widely …
Study of surfactant combinations and development of a novel nanoemulsion for minimising variations in bioavailability of ezetimibe
The present study aimed at develo** an optimal nanoemulsion of ezetimibe and
evaluating its stability, pharmacodynamic and pharmacokinetic potential. Solubility of …
evaluating its stability, pharmacodynamic and pharmacokinetic potential. Solubility of …
Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion
The purpose of this research was to evaluate the effect of the HPC (hydroxypropylcellulose)
and Tween 80 on the physicochemical properties and oral bioavailability of ezetimibe …
and Tween 80 on the physicochemical properties and oral bioavailability of ezetimibe …
Nanocarrier for the enhanced bioavailability of a cardiovascular agent: in vitro, pharmacodynamic, pharmacokinetic and stability assessment
The goals of the current study were to develop and characterize a nanoemulsion of
ezetimibe, evaluate its stability, lipid lowering and pharmacokinetic profile. Solubility of the …
ezetimibe, evaluate its stability, lipid lowering and pharmacokinetic profile. Solubility of the …
Design and evaluation of combined atorvastatin and ezetimibe optimized self-nano emulsifying drug delivery system
The purpose was to develop, optimize and assess Self-nanoemulsifying drug delivery
system (SNEDDS) to enhance solubility and dissolution rate of the poorly-water soluble …
system (SNEDDS) to enhance solubility and dissolution rate of the poorly-water soluble …
Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe
Background The objective of this study was to compare the physicochemical characteristics,
solubility, dissolution, and oral bioavailability of an ezetimibe-loaded solid self …
solubility, dissolution, and oral bioavailability of an ezetimibe-loaded solid self …
Mechanism of drug-drug interactions between warfarin and statins
AN Shaik, T Bohnert, DA Williams, LL Gan… - Journal of …, 2016 - Elsevier
The anticoagulant drug warfarin and the lipid-lowering statin drugs are commonly co-
administered to patients with cardiovascular diseases. Clinically significant drug-drug …
administered to patients with cardiovascular diseases. Clinically significant drug-drug …
Development and validation of a LC–MS/MS assay for quantification of cisplatin in rat plasma and urine
Till date, no analytical method published to detect Cisplatin has been validated according to
the US Food and Drug Administration (FDA) guidance using liquid chromatography mass …
the US Food and Drug Administration (FDA) guidance using liquid chromatography mass …
Ezetimibe ketone protects against renal ischemia–reperfusion injury and attenuates oxidative stress via activation of the Nrf2/HO‐1 signaling pathway
Z Chen, K Wang, X He, D Xue… - Journal of Biochemical …, 2024 - Wiley Online Library
Recently, ezetimibe (EZM) has been suggested to be a potent Nrf2 activator that is important
for preventing oxidative stress. Interestingly, we found that its metabolite ezetimibe ketone …
for preventing oxidative stress. Interestingly, we found that its metabolite ezetimibe ketone …