Health risks associated with the pharmaceuticals in wastewater

N Nassiri Koopaei, M Abdollahi - DARU Journal of Pharmaceutical …, 2017 - Springer
The overwhelming population growth in recent decades and water crisis along with limited
and uneven geographical distribution of fresh water resources is a growing challenge for the …

Bioanalysis in drug discovery and development

S Pandey, P Pandey, G Tiwari, R Tiwari - Pharmaceutical methods, 2010 - Elsevier
Recent years have witnessed the introduction of several high-quality review articles into the
literature covering various scientific and technical aspects of bioanalysis. Now it is widely …

Study of surfactant combinations and development of a novel nanoemulsion for minimising variations in bioavailability of ezetimibe

V Bali, M Ali, J Ali - Colloids and Surfaces B: Biointerfaces, 2010 - Elsevier
The present study aimed at develo** an optimal nanoemulsion of ezetimibe and
evaluating its stability, pharmacodynamic and pharmacokinetic potential. Solubility of …

Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion

R Rashid, DW Kim, F ud Din, O Mustapha… - Carbohydrate …, 2015 - Elsevier
The purpose of this research was to evaluate the effect of the HPC (hydroxypropylcellulose)
and Tween 80 on the physicochemical properties and oral bioavailability of ezetimibe …

Nanocarrier for the enhanced bioavailability of a cardiovascular agent: in vitro, pharmacodynamic, pharmacokinetic and stability assessment

V Bali, M Ali, J Ali - International journal of pharmaceutics, 2011 - Elsevier
The goals of the current study were to develop and characterize a nanoemulsion of
ezetimibe, evaluate its stability, lipid lowering and pharmacokinetic profile. Solubility of the …

Design and evaluation of combined atorvastatin and ezetimibe optimized self-nano emulsifying drug delivery system

AR Gardouh, AM Nasef, Y Mostafa, S Gad - Journal of Drug Delivery …, 2020 - Elsevier
The purpose was to develop, optimize and assess Self-nanoemulsifying drug delivery
system (SNEDDS) to enhance solubility and dissolution rate of the poorly-water soluble …

Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe

R Rashid, DW Kim, AM Yousaf… - International journal …, 2015 - Taylor & Francis
Background The objective of this study was to compare the physicochemical characteristics,
solubility, dissolution, and oral bioavailability of an ezetimibe-loaded solid self …

Mechanism of drug-drug interactions between warfarin and statins

AN Shaik, T Bohnert, DA Williams, LL Gan… - Journal of …, 2016 - Elsevier
The anticoagulant drug warfarin and the lipid-lowering statin drugs are commonly co-
administered to patients with cardiovascular diseases. Clinically significant drug-drug …

Development and validation of a LC–MS/MS assay for quantification of cisplatin in rat plasma and urine

AN Shaik, DA Altomare, LJ Lesko, MN Trame - Journal of Chromatography …, 2017 - Elsevier
Till date, no analytical method published to detect Cisplatin has been validated according to
the US Food and Drug Administration (FDA) guidance using liquid chromatography mass …

Ezetimibe ketone protects against renal ischemia–reperfusion injury and attenuates oxidative stress via activation of the Nrf2/HO‐1 signaling pathway

Z Chen, K Wang, X He, D Xue… - Journal of Biochemical …, 2024 - Wiley Online Library
Recently, ezetimibe (EZM) has been suggested to be a potent Nrf2 activator that is important
for preventing oxidative stress. Interestingly, we found that its metabolite ezetimibe ketone …