Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …

In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …

MicroRNAs (miRNAs) are noncoding RNAs that have been identified as important
posttranscriptional regulators of gene expression. miRNAs production is controlled at …

MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …

Cancer has become the second greatest cause of death worldwide. Although there are
several different classes of anticancer drugs that are available in clinic, some tough issues …

Cancer is a complex disease, and its study requires deep understanding of several
biological processes and their regulation. It is an accepted fact that non-coding RNAs are …

Apoptosis deficiency is one of the most important features observed in neoplastic diseases.
The Bcl-2 family is composed of a subset of proteins that act as decisive apoptosis …

Since the discovery of the first microRNA (miRNA), the exploration of miRNA biology has
come to a new era in recent decades. Monumental studies have proven that miRNAs can be …

The emergence of targeted therapy for patients with hematological diseases has
permanently altered the therapeutic landscape. Immunochemotherapy regimes are now …

Circular RNAs (circRNAs) are a large class of noncoding RNAs, generated from a process
called back-splicing, that possess critical regulatory functions in many cellular events. A …