Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants
The spike glycoprotein of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …
continues to accumulate substitutions, leading to breakthrough infections of vaccinated …
Randomized controlled trial reveals no benefit to a 3-month delay in COVID-19 mRNA booster vaccine
BACKGROUND There is uncertainty about the timing of booster vaccination against COVID-
19 in highly vaccinated populations during the present endemic phase of COVID-19. Studies …
19 in highly vaccinated populations during the present endemic phase of COVID-19. Studies …
Durability of humoral and cellular immunity six months after the BNT162b2 bivalent booster
Studies about the duration of the humoral and cellular response following the bivalent
booster administration are still scarce. We aimed at assessing the humoral and cellular …
booster administration are still scarce. We aimed at assessing the humoral and cellular …
[HTML][HTML] Evaluating the Quality of Studies Assessing COVID-19 Vaccine Neutralizing Antibody Immunogenicity
M Katzmarzyk, R Naughton, I Sitaras, H Jacobsen… - Vaccines, 2024 - mdpi.com
Objective: COVID-19 vaccine-neutralizing antibodies provide early data on potential vaccine
effectiveness, but their usefulness depends on study reliability and reporting quality …
effectiveness, but their usefulness depends on study reliability and reporting quality …
Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates
The ongoing evolution of the SARS-CoV-2 virus has led to a move to update vaccine
antigens in 2022 and 2023. These updated antigens were chosen and approved based …
antigens in 2022 and 2023. These updated antigens were chosen and approved based …
SARS-CoV-2 mucosal neutralising immunity after vaccination
EJ Carr, G Dowgier, D Greenwood… - The Lancet Infectious …, 2024 - thelancet.com
Mucosal vaccines that prevent SARS-CoV-2 infection might provide benefits beyond existing
intramuscularly administered vaccines: through enhanced individual-level protection against …
intramuscularly administered vaccines: through enhanced individual-level protection against …
Real-time estimation of immunological responses against emerging SARS-CoV-2 variants in the UK: a mathematical modelling study
Background The emergence of SARS-CoV-2 variants and COVID-19 vaccination have
resulted in complex exposure histories. Rapid assessment of the effects of these exposures …
resulted in complex exposure histories. Rapid assessment of the effects of these exposures …
A bivalent COVID-19 mRNA vaccine elicited broad immune responses and protection against Omicron subvariants infection
Abstract Continuously emerging SARS-CoV-2 Omicron subvariants pose a threat thwarting
the effectiveness of approved COVID-19 vaccines. Especially, the protection breadth and …
the effectiveness of approved COVID-19 vaccines. Especially, the protection breadth and …
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion
Coronaviruses express their structural and accessory genes via a set of subgenomic RNAs,
whose synthesis is directed by transcription regulatory sequences (TRSs) in the 5 …
whose synthesis is directed by transcription regulatory sequences (TRSs) in the 5 …
Divergent performance of vaccines in the UK autumn 2023 COVID-19 booster campaign
M Shawe-Taylor, D Greenwood, A Hobbs, G Dowgier… - The Lancet, 2024 - thelancet.com
On Dec 13, 2023, WHO's Technical Advisory Group on COVID-19 Vaccine Composition
(TAG-CO-VAC) reiterated their guidance1 from May, 2023, recommending updating …
(TAG-CO-VAC) reiterated their guidance1 from May, 2023, recommending updating …