Advances in olfaction-inspired biomaterials applied to bioelectronic noses

T Wasilewski, J Gębicki, W Kamysz - Sensors and Actuators B: Chemical, 2018 - Elsevier
Among all the senses, olfactory system of mammals is the least characterised as far as the
mechanisms of odour identification are concerned. The results of recent investigations allow …

The potential of in vitro neuronal networks cultured on micro electrode arrays for biomedical research

M Cerina, MC Piastra, M Frega - Progress in Biomedical …, 2023 - iopscience.iop.org
In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …

The MNK–eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain

JK Moy, A Khoutorsky, MN Asiedu… - Journal of …, 2017 - Soc Neuroscience
Injury-induced sensitization of nociceptors contributes to pain states and the development of
chronic pain. Inhibiting activity-dependent mRNA translation through mechanistic target of …

Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set

ER McConnell, MA McClain, J Ross, WR LeFew… - Neurotoxicology, 2012 - Elsevier
Microelectrode array (MEA) approaches have been proposed as a tool for detecting
functional changes in electrically excitable cells, including neurons, exposed to drugs …

A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing

A Vassallo, M Chiappalone, RDC Lopes, B Scelfo… - Neurotoxicology, 2017 - Elsevier
There is a need for methods to screen and prioritize chemicals for potential hazard,
including neurotoxicity. Microelectrode array (MEA) systems enable simultaneous …

In vitro electrophysiological drug testing on neuronal networks derived from human induced pluripotent stem cells

G Parodi, G Zanini, L Collo, R Impollonia… - Stem Cell Research & …, 2024 - Springer
Background In vitro models for drug testing constitute a valuable and simplified in-vivo-like
assay to better comprehend the biological drugs effect. In particular, the combination of …

Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone

Z Cao, S Hulsizer, F Tassone, H Tang… - Human molecular …, 2012 - academic.oup.com
Premutation CGG repeat expansions (55–200 CGG repeats; preCGG) within the fragile X
mental retardation 1 (FMR1) gene cause fragile X-associated tremor/ataxia syndrome …

Assessment of spontaneous neuronal activity in vitro using multi-well multi-electrode arrays: implications for assay development

J Negri, V Menon, TL Young-Pearse - ENeuro, 2020 - eneuro.org
Multi-electrode arrays (MEAs) are being more widely used by researchers as an instrument
platform for monitoring prolonged, non-destructive recordings of spontaneously firing …

A neuromorphic prosthesis to restore communication in neuronal networks

S Buccelli, Y Bornat, I Colombi, M Ambroise, L Martines… - IScience, 2019 - cell.com
Recent advances in bioelectronics and neural engineering allowed the development of
brain machine interfaces and neuroprostheses, capable of facilitating or recovering …

Integration of toxicodynamic and toxicokinetic new approach methods into a weight-of-evidence analysis for pesticide developmental neurotoxicity assessment: A …

S Dobreniecki, E Mendez, A Lowit… - Regulatory Toxicology …, 2022 - Elsevier
Abstract DL-glufosinate ammonium (DL-GLF) is a registered herbicide for which a guideline
Developmental Neurotoxicity (DNT) study has been conducted. Offspring effects included …