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Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review
Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …
healthcare services. In the hospital, it is associated with resistance to several antibiotics …
Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections
NM Maurice, B Bedi, RT Sadikot - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a major health challenge that causes recalcitrant multidrug-
resistant infections, especially in immunocompromised and hospitalized patients. P …
resistant infections, especially in immunocompromised and hospitalized patients. P …
The role of bacterial biofilms in chronic infections
T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …
100 years. These infections killed millions of people in previous centuries, but they have …
[HTML][HTML] The association between biofilm formation and antimicrobial resistance with possible ingenious bio-remedial approaches
Y Dutt, R Dhiman, T Singh, A Vibhuti, A Gupta… - Antibiotics, 2022 - mdpi.com
Biofilm has garnered a lot of interest due to concerns in various sectors such as public
health, medicine, and the pharmaceutical industry. Biofilm-producing bacteria show a …
health, medicine, and the pharmaceutical industry. Biofilm-producing bacteria show a …
Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors
At present, anti-virulence drugs are being considered as potential therapeutic alternatives
and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit …
and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit …
Exploiting quorum sensing to confuse bacterial pathogens
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …
is used to coordinate gene expression among local populations. Its use by bacterial …
Quorum sensing inhibitors: an overview
VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …
emergence of multiple drug resistant strains. Most infectious diseases are caused by …
Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways
Numerous species of bacteria employ a mechanism of intercellular communication known
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …
Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …
Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo
G Brackman, P Cos, L Maes, HJ Nelis… - Antimicrobial agents …, 2011 - journals.asm.org
Although the exact role of quorum sensing (QS) in various stages of biofilm formation,
maturation, and dispersal and in biofilm resistance is not entirely clear, the use of QS …
maturation, and dispersal and in biofilm resistance is not entirely clear, the use of QS …