Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Primary sclerosing cholangitis (PSC) offers unique opportunities to explore the gut–liver axis
owing to the close association between liver disease and colonic inflammation. It is well …

Humans possess abundant amounts of microorganisms, including bacteria, fungi, viruses,
and archaea, in their gut. Patients with nonalcoholic fatty liver disease (NAFLD) exhibit …

Nonalcoholic fatty liver disease (NAFLD) poses an emerging threat topublic health.
Nonalcoholic steatohepatitis (NASH) is reported to be the most rapidly rising cause of …

Primary sclerosing cholangitis (PSC) is characterized by progressive biliary inflammation
and fibrosis. Although gut commensals are associated with PSC, their causative roles and …

Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …

Background The gut virome has been implicated in inflammatory bowel disease (IBD), yet a
full understanding of the gut virome in IBD patients, especially across diverse geographic …

Reference genomes are essential for analyzing the metabolic and functional potentials of
microbiomes. However, microbial genome resources are limited because most of …

The gut microbiota composition is important for nutrient metabolism, mucosal barrier
function, immunomodulation, and defense against pathogens. Alterations in the gut …