Current understanding of hypoxia in glioblastoma multiforme and its response to immunotherapy
Simple Summary Glioblastoma multiforme (GBM) is the most aggressive tumor type in the
central nervous system. Hypoxia, defined as a lack of sufficient oxygen in tissues, is the most …
central nervous system. Hypoxia, defined as a lack of sufficient oxygen in tissues, is the most …
Targeting the dendritic cell-T cell axis to develop effective immunotherapies for glioblastoma
Glioblastoma is an aggressive primary brain tumor that has seen few advances in treatments
for over 20 years. In response to this desperate clinical need, multiple immunotherapy …
for over 20 years. In response to this desperate clinical need, multiple immunotherapy …
BODIPY-based NO probe for macrophage-targeted immunotherapy response monitoring
X Li, H Chen, Y Wang, H Chen, Y Gao - Analytical Chemistry, 2023 - ACS Publications
Precise and rapid detection of immune responses is critical for timely therapeutic regimen
adjustment. Immunomodulation of tumor-associated macrophages (TAMs) from a …
adjustment. Immunomodulation of tumor-associated macrophages (TAMs) from a …
Alternative CAR therapies: recent approaches in engineering chimeric antigen receptor immune cells to combat cancer
For nearly three decades, chimeric antigen receptors (CARs) have captivated the interest of
researchers seeking to find novel immunotherapies to treat cancer. CARs were first …
researchers seeking to find novel immunotherapies to treat cancer. CARs were first …
Glioblastoma treatment: state-of-the-art and future perspectives
A Rodríguez-Camacho, JG Flores-Vázquez… - International journal of …, 2022 - mdpi.com
(1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central
nervous system. Through many years, research has brought various advances in …
nervous system. Through many years, research has brought various advances in …
Prognostic value and immune relevancy of a combined autophagy-, apoptosis-and necrosis-related gene signature in glioblastoma
Y Bi, ZH Wu, F Cao - BMC cancer, 2022 - Springer
Background Glioblastoma (GBM) is considered the most malignant and devastating
intracranial tumor without effective treatment. Autophagy, apoptosis, and necrosis, three …
intracranial tumor without effective treatment. Autophagy, apoptosis, and necrosis, three …
Combination nanochemotherapy of brain tumor using polymeric nanoparticles loaded with doxorubicin and paclitaxel: An in vitro and in vivo study
This study aims to overcome physiological barriers and increase the therapeutic index for
the treatment of glioblastoma (GBM) tumors by using Paclitaxel (PTX) loaded Poly (lactic co …
the treatment of glioblastoma (GBM) tumors by using Paclitaxel (PTX) loaded Poly (lactic co …
Sulforaphane causes cell cycle arrest and apoptosis in human glioblastoma U87MG and U373MG cell lines under hypoxic conditions
Glioblastoma multiforme (GBM) is the most prevalent and aggressive primary brain tumor.
The median survival rate from diagnosis ranges from 15 to 17 months because the tumor is …
The median survival rate from diagnosis ranges from 15 to 17 months because the tumor is …
The Inhibitory Effects of Terminalia catappa L. Extract on the Migration and Invasion of Human Glioblastoma Multiforme Cells
HH Chung, MJ Hsieh, YS Hsieh, PN Chen, CP Ko… - Pharmaceuticals, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is one of the most aggressive and common types of brain
tumor. Due to its high proliferation ability, a high lethality rate has been observed with this …
tumor. Due to its high proliferation ability, a high lethality rate has been observed with this …
[HTML][HTML] Immunotherapy reverses glioma-driven dysfunction of immune system homeostasis
Background Glioma-induced immune dysregulation of the hematopoietic system has been
described in a limited number of studies. In this study, our group further demonstrates that …
described in a limited number of studies. In this study, our group further demonstrates that …