The blood vessels supplying tumors are strikingly heterogeneous and differ from their
normal counterparts with respect to organization, structure, and function. Six distinctly …

Glioma is recognized as a highly angiogenic malignant brain tumor. Vasculogenic mimicry
(VM) greatly restricts the therapeutic effect of anti-angiogenic tumor therapy for glioma …

Purpose Vasculogenic mimicry patterns, formed by highly invasive melanoma cells, connect
to endothelial cell-lined blood vessels and contain fluid in vitroand in vivo. This study was …

Antiangiogenesis therapy is one of the most promising approaches to cancer treatment. Its
clinical success has come out but still too limited. Vascularization of tumor is a complex and …

methods. A 15-μL suspension of metastatic MUM2B or either primary OCM1 or M619 uveal
melanoma cells was injected into the liver parenchyma of 105 CB17 SCID mice through a 1 …

Background/Aim: Human mesenchymal stem cells (hMSC) represent a versatile cell
population, able to modulate the tumor microenvironment. Our aim was to recreate an open …

The present disclosure relates generally to systems and methods useful in medicine, cellular
biology, nanotechnol ogy, and cell culturing. In particular, at least in some embodi ments, the …

Recent advance in three-dimensional (3D) imaging technology allows us to inspect visually
and quantitatively the architecture of complex biological tissues and pathological lesions …

Purpose: Prognostic predictors in uveal melanoma (UM) consist of clinical,
histomorphologic, and genetic features. Vascular lakes (VLs) are immature blood vessels …

Previously, we focused on multi-root development of the upper and lower molars in mice
with the aid of three-dimensional (3D) reconstruction technologies. ICR mice, 3 to 28 days …