Prolonged low-grade inflammation or smoldering inflammation is a hallmark of a cancer.
Eosinophils are components of the immune microenvironment that modulates tumor …

Prognostic biomarkers are of great significance to predict the outcome of patients with
cancer, to guide the clinical treatments, to elucidate tumorigenesis mechanisms, and offer …

Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC).
Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT …

Aim: To develop a web tool for survival analysis based on CpG methylation patterns.
Materials & methods: We utilized methylome data from 'The Cancer Genome Atlas' and used …

Psychological distress has long been suspected to influence cancer incidence and mortality.
It remains largely unknown whether and how stress affects the efficacy of anticancer …

WNT2 acts as a pro-angiogenic factor in placental vascularization and increases
angiogenesis in liver sinusoidal endothelial cells (ECs) and other ECs. Increased WNT2 …

Mutations in isocitrate dehydrogenases (IDH) are oncogenic events due to the generation of
oncogenic metabolite 2-hydroxyglutarate. However, the role of wild-type IDH in cancer …

Purpose: Blockade of the PD-1/PD-L1 axis emerged as a promising new therapeutic option
for cancer that has resulted in lasting responses in metastatic renal, lung carcinomas, and …

Drug resistance is the main obstacle in the improvement of chemotherapeutic efficacy in
glioblastoma. Previously, we showed that dehydroepiandrosterone (DHEA), one kind of …

An integrative multi-omics database is needed urgently, because focusing only on analysis
of one-dimensional data falls far short of providing an understanding of cancer. Previously …