[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

Design strategies for water-soluble small molecular chromogenic and fluorogenic probes

X Li, X Gao, W Shi, H Ma - Chemical reviews, 2014 - ACS Publications
Chromogenic and fluorogenic probes may be described as the reagents that can interact
with analytes (targets) accompanied by the changes of their spectroscopic (chromogenic, or …

The new biology and pharmacology of glucagon

TD Müller, B Finan, C Clemmensen… - Physiological …, 2017 - journals.physiology.org
In the last two decades we have witnessed sizable progress in defining the role of
gastrointestinal signals in the control of glucose and energy homeostasis. Specifically, the …

New fluorescent chemosensors for metal ions in solution

M Formica, V Fusi, L Giorgi, M Micheloni - Coordination Chemistry Reviews, 2012 - Elsevier
After a brief introduction on the main transduction mechanisms for metal ion detection by
fluorescence, this paper reviews ligand molecules containing fluorophores synthesized and …

The functions of metamorphic metallothioneins in zinc and copper metabolism

A Krężel, W Maret - International journal of molecular sciences, 2017 - mdpi.com
Recent discoveries in zinc biology provide a new platform for discussing the primary
physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc …

Fluorescent chemosensors for Zn2+

Z Xu, J Yoon, DR Spring - Chemical Society Reviews, 2010 - pubs.rsc.org
In the past decade, fluorescent chemosensors for zinc ion (Zn2+) have attracted great
attention because of the biological significance of zinc combined with the simplicity and high …

Metals in neurobiology: probing their chemistry and biology with molecular imaging

EL Que, DW Domaille, CJ Chang - Chemical reviews, 2008 - ACS Publications
The brain is a singular organ of unique biological complexity that serves as the command
center for cognitive and motor function. As such, this specialized system also possesses a …

Fluorescence imaging of metal ions implicated in diseases

X Qian, Z Xu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal ions play an important role in various biological processes, their abnormal
homeostasis in cells is related to many diseases, such as neurodegenerative disease …

Synthetic fluorescent sensors for studying the cell biology of metals

DW Domaille, EL Que, CJ Chang - Nature chemical biology, 2008 - nature.com
Metals are essential for sustaining all forms of life, but alterations in their cellular
homeostasis are connected to severe human disorders, including cancer, diabetes and …

Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors

P Jiang, Z Guo - Coordination chemistry reviews, 2004 - Elsevier
Zinc is an essential biological element for living organisms and fluorescent imaging has
been proven to be the most suitable technique for its in vivo monitoring. From the late 1980s …