[HTML][HTML] Role of structural and non-structural proteins and therapeutic targets of SARS-CoV-2 for COVID-19
Coronavirus belongs to the family of Coronaviridae, comprising single-stranded, positive-
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …
sense RNA genome (+ ssRNA) of around 26 to 32 kilobases, and has been known to cause …
SARS-CoV-2 accessory proteins in viral pathogenesis: knowns and unknowns
There are still many unanswered questions concerning viral SARS-CoV-2 pathogenesis in
COVID-19. Accessory proteins in SARS-CoV-2 consist of eleven viral proteins whose roles …
COVID-19. Accessory proteins in SARS-CoV-2 consist of eleven viral proteins whose roles …
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population
Convalescent plasma is a leading treatment for coronavirus disease 2019 (COVID-19), but
there is a paucity of data identifying its therapeutic efficacy. Among 126 potential …
there is a paucity of data identifying its therapeutic efficacy. Among 126 potential …
The proteins of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2 or n-COV19), the cause of COVID-19
FK Yoshimoto - The protein journal, 2020 - Springer
The devastating effects of the recent global pandemic (termed COVID-19 for “coronavirus
disease 2019”) caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV …
disease 2019”) caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV …
[HTML][HTML] The coding capacity of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing
coronavirus disease 2019 (COVID-19) pandemic 1. To understand the pathogenicity and …
coronavirus disease 2019 (COVID-19) pandemic 1. To understand the pathogenicity and …
[HTML][HTML] SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
NS Ogando, TJ Dalebout… - Journal of General …, 2020 - microbiologyresearch.org
The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread …
at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread …
Coronaviruses post-SARS: update on replication and pathogenesis
Although coronaviruses were first identified nearly 60 years ago, they only received notoriety
in 2003 when one of their members was identified as the aetiological agent of severe acute …
in 2003 when one of their members was identified as the aetiological agent of severe acute …
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design
B Malone, N Urakova, EJ Snijder… - … Reviews Molecular Cell …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed millions of
people and continues to cause massive global upheaval. Coronaviruses are positive-strand …
people and continues to cause massive global upheaval. Coronaviruses are positive-strand …
[HTML][HTML] SARS-CoV-2 suppresses IFNβ production mediated by NSP1, 5, 6, 15, ORF6 and ORF7b but does not suppress the effects of added interferon
M Shemesh, TE Aktepe, JM Deerain, JL McAuley… - PLoS …, 2021 - journals.plos.org
Type I Interferons (IFN-Is) are a family of cytokines which play a major role in inhibiting viral
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …
infection. Resultantly, many viruses have evolved mechanisms in which to evade the IFN-I …
Structure and function of major SARS-CoV-2 and SARS-CoV proteins
SARS-CoV-2 virus, the causative agent of COVID-19 pandemic, has a genomic organization
consisting of 16 nonstructural proteins (nsps), 4 structural proteins, and 9 accessory …
consisting of 16 nonstructural proteins (nsps), 4 structural proteins, and 9 accessory …