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Functional characterization of human pluripotent stem cell-derived models of the brain with microelectrode arrays
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …
[HTML][HTML] Neuromorphic-based neuroprostheses for brain rewiring: state-of-the-art and perspectives in neuroengineering
Neuroprostheses are neuroengineering devices that have an interface with the nervous
system and supplement or substitute functionality in people with disabilities. In the collective …
system and supplement or substitute functionality in people with disabilities. In the collective …
Loss of neuron network coherence induced by virus-infected astrocytes: a model study
Coherent activations of brain neuron networks underlie many physiological functions
associated with various behavioral states. These synchronous fluctuations in the electrical …
associated with various behavioral states. These synchronous fluctuations in the electrical …
Design of Cultured Neuron Networks in vitro with Predefined Connectivity Using Asymmetric Microfluidic Channels
The architecture of neuron connectivity in brain networks is one of the basic mechanisms by
which to organize and sustain a particular function of the brain circuitry. There are areas of …
which to organize and sustain a particular function of the brain circuitry. There are areas of …
Impact of modular organization on dynamical richness in cortical networks
H Yamamoto, S Moriya, K Ide, T Hayakawa… - Science …, 2018 - science.org
As in many naturally formed networks, the brain exhibits an inherent modular architecture
that is the basis of its rich operability, robustness, and integration-segregation capacity …
that is the basis of its rich operability, robustness, and integration-segregation capacity …
Modular microstructure design to build neuronal networks of defined functional connectivity
Theoretical and in vivo neuroscience research suggests that functional information transfer
within neuronal networks is influenced by circuit architecture. Due to the dynamic …
within neuronal networks is influenced by circuit architecture. Due to the dynamic …
On the road to the brain-on-a-chip: a review on strategies, methods, and applications
The brain is the most complex organ of our body. Such a complexity spans from the single-
cell morphology up to the intricate connections that hundreds of thousands of neurons …
cell morphology up to the intricate connections that hundreds of thousands of neurons …
Electrophysiology read-out tools for brain-on-Chip biotechnology
Brain-on-Chip (BoC) biotechnology is emerging as a promising tool for biomedical and
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …
Structure-function dynamics of engineered, modular neuronal networks with controllable afferent-efferent connectivity
N Winter-Hjelm, ÅB Tomren, P Sikorski… - Journal of Neural …, 2023 - iopscience.iop.org
Objective. Microfluidic devices interfaced with microelectrode arrays have in recent years
emerged as powerful platforms for studying and manipulating in vitro neuronal networks at …
emerged as powerful platforms for studying and manipulating in vitro neuronal networks at …
A neuromorphic prosthesis to restore communication in neuronal networks
Recent advances in bioelectronics and neural engineering allowed the development of
brain machine interfaces and neuroprostheses, capable of facilitating or recovering …
brain machine interfaces and neuroprostheses, capable of facilitating or recovering …