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A comprehensive review on fused heterocyclic as DNA intercalators: promising anticancer agents
Since the discovery of DNA intercalating agents (by Lerman, 1961), a growing number of
organic, inorganic, and metallic compounds have been developed to treat life-threatening …
organic, inorganic, and metallic compounds have been developed to treat life-threatening …
Intercalation of Organic Dye Molecules into Double‐stranded DNA. Part 2: The Annelated Quinolizinium Ion as a Structural Motif in DNA Intercalators†
H Ihmels, K Faulhaber, D Vedaldi… - Photochemistry and …, 2005 - Wiley Online Library
ABSTRACT DNA intercalators represent an important class of compounds with a high
potential as DNA‐targeting drugs. In this review it is demonstrated that annelated …
potential as DNA‐targeting drugs. In this review it is demonstrated that annelated …
A general method to diverse cinnolines and cinnolinium salts.
D Zhao, Q Wu, X Huang, F Song… - Chemistry-A European …, 2013 - search.ebscohost.com
Rhodium catalysis: A highly efficient and general method has been established to prepare
cinnolines, cinnolinium salts, and polycyclic cinnolinium salts through the rhodium (III) …
cinnolines, cinnolinium salts, and polycyclic cinnolinium salts through the rhodium (III) …
Cinnoline derivatives with biological activity
W Lewgowd, A Stanczak - Archiv der Pharmazie: An …, 2007 - Wiley Online Library
Although cinnoline belongs to a family of fairly well known heterocycles, the interest in the
study of its derivatives continues. Cinnoline compounds demonstrate interesting bioactivity …
study of its derivatives continues. Cinnoline compounds demonstrate interesting bioactivity …
An environmentally benign cascade reaction of chromone-3-carboxaldehydes with ethyl 2-(pyridine-2-yl) acetate derivatives for highly site-selective synthesis of …
L Chen, R Huang, K Li, XH Yun, CL Yang, SJ Yan - Green Chemistry, 2020 - pubs.rsc.org
A novel protocol for the synthesis of quinolizines (3) and quinolizinium salts (4) from
chromone-3-carboxaldehydes 1 with ethyl 2-(pyridine-2-yl) acetate derivatives 2via an …
chromone-3-carboxaldehydes 1 with ethyl 2-(pyridine-2-yl) acetate derivatives 2via an …
An improved synthesis of α-carbolines under microwave irradiation
P Vera-Luque, R Alajarín, J Alvarez-Builla… - Organic …, 2006 - ACS Publications
α-Carbolines are interesting core structures for designing DNA-interacting small molecules.
However, these compounds are not commercially available and their synthetic methods are …
However, these compounds are not commercially available and their synthetic methods are …
Synthesis of new quinolizinium-based fluorescent compounds and studies on their applications in photocatalysis
WM Yip, Q Yu, A Tantipanjaporn, WC Chan… - Organic & …, 2021 - pubs.rsc.org
Quinoliziniums, cationic aromatic heterocycles bearing a quaternary bridgehead nitrogen,
have been widely used as fluorescent dyes, DNA intercalators, ionic liquids etc. A library of …
have been widely used as fluorescent dyes, DNA intercalators, ionic liquids etc. A library of …
A QM/MM study of the absorption spectrum of harmane in water solution and interacting with DNA: the crucial role of dynamic effects
We present a time-dependent density functional theory computation of the absorption
spectra of one β-carboline system: the harmane molecule in its neutral and cationic forms …
spectra of one β-carboline system: the harmane molecule in its neutral and cationic forms …
Benzo[f]azino[2,1-a]phthalazinium Cations: Novel DNA Intercalating Chromophores with Antiproliferative Activity
V Martínez, C Burgos, J Alvarez-Builla… - Journal of medicinal …, 2004 - ACS Publications
New azaquinolizinium-type cations have been obtained from isochromane. The synthesis
was completed over seven steps and included as the key feature an intramolecular …
was completed over seven steps and included as the key feature an intramolecular …
The application of azoarenes in the synthesis of nitrogen-containing heterocycles
AZ Halimehjani, N Sadeghzadeh, S Moghaddam - Tetrahedron, 2024 - Elsevier
Azoarenes are efficient intermediates in synthetic organic chemistry. In this review, the
application of azoarenes for the synthesis of nitrogen-containing heterocyles including …
application of azoarenes for the synthesis of nitrogen-containing heterocyles including …