Methods Specific studies and articles were reviewed to illustrate what the test measures, to
evaluate its sensitivity to change, and to discuss its use in clinical practice. Results The …

BackgroundThis review aimed to address the question of whether cognitive impairment
should be considered a core feature of depression that may be a valuable target for …

Background Findings from clinical trials of proprotein convertase subtilisin–kexin type 9
(PCSK9) inhibitors have led to concern that these drugs or the low levels of low-density …

Background This review provides an overview of obsessive‐compulsive disorder (OCD)
symptoms, including the four partially distinct subtypes of the disorder, current diagnostic …

Brain dopamine (DA) has long been implicated in cognitive control processes, including
working memory. However, the precise role of DA in cognition is not well-understood, partly …

We review the findings of systematic reviews and meta-analyses of case-control studies that
examine brain functioning and cognitive correlates of adolescent cannabis use using …

Research into the heterogeneous nature of cognitive impairment documented in patients
with Parkinson's disease (PD) has focused on disentangling deficits that vary between …

Executive functions (EFs) make possible mentally playing with ideas; taking the time to think
before acting; meeting novel, unanticipated challenges; resisting temptations; and staying …

Abstract 'Brain training', or the goal of improved cognitive function through the regular use of
computerized tests, is a multimillion-pound industry, yet in our view scientific evidence to …

Cognitive impairment in patients with Parkinson's disease is gaining increased clinical
significance owing to the relative success of therapeutic approaches to the motor symptoms …