[HTML][HTML] Cannabinoids and epilepsy

EC Rosenberg, RW Tsien, BJ Whalley, O Devinsky - Neurotherapeutics, 2015 - Elsevier
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …

International Union of Pharmacology. XXVII. Classification of cannabinoid receptors

AC Howlett, F Barth, TI Bonner, G Cabral… - Pharmacological …, 2002 - Elsevier
Two types of cannabinoid receptor have been discovered so far, CB 1 (2.1: CBD: 1: CB1:),
cloned in 1990, and CB 2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …

[KNJIGA][B] Environmental psychology for design

D Kopec - 2018 - books.google.com
How does a room affect an occupant's behavior and well-being? How does a building
influence its residents' health? Environmental Psychology for Design, 3rd Edition, explores …

[HTML][HTML] Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity

EC Rosenberg, S Chamberland, M Bazelot, ER Nebet… - Neuron, 2023 - cell.com
Summary Cannabidiol (CBD), a non-euphoric component of cannabis, reduces seizures in
multiple forms of pediatric epilepsies, but the mechanism (s) of anti-seizure action remain …

Neuronal activity determines distinct gliotransmitter release from a single astrocyte

A Covelo, A Araque - elife, 2018 - elifesciences.org
Accumulating evidence indicates that astrocytes are actively involved in brain function by
regulating synaptic activity and plasticity. Different gliotransmitters, such as glutamate, ATP …

[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission

M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

The molecular logic of endocannabinoid signalling

D Piomelli - Nature Reviews Neuroscience, 2003 - nature.com
The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …

[HTML][HTML] Role of endogenous cannabinoids in synaptic signaling

TF Freund, I Katona, D Piomelli - Physiological reviews, 2003 - journals.physiology.org
Freund, Tamás F., István Katona, and Daniele Piomelli. Role of Endogenous Cannabinoids
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …

Cannabis and the brain

L Iversen - Brain, 2003 - academic.oup.com
The active compound in herbal cannabis, Δ9‐tetrahydrocannabinol, exerts all of its known
central effects through the CB1 cannabinoid receptor. Research on cannabinoid …

Dendritic excitability and synaptic plasticity

PJ Sjostrom, EA Rancz, A Roth… - Physiological …, 2008 - journals.physiology.org
Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …