Functional nucleic acid (NA)-based drugs have a broad range of applications since they
allow the alteration and control of gene/protein expression patterns in cells. In principle …

Aptamers with high affinity and specificity for certain targets have rapidly become a novel
class of targeted ligands applicated in drug delivery. Based on the excellent characteristics …

Lipid-based nanocarriers have been extensively investigated for their application in drug
delivery. Particularly, liposomes are now clinically established for treating various diseases …

Colorectal Cancer (CRC) is one of the leading causes of cancer-related deaths worldwide.
Despite the notable advances achieved over the last few decades, CRC remains a hard-to …

Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

In recent years, the field of drug delivery has witnessed remarkable progress, driven by the
quest for more effective and precise therapeutic interventions. Among the myriad strategies …

Multidrug resistance (MDR) of tumors is one of the main reasons for the failure of
chemotherapy. Multidrug resistance refers to the cross-resistance of tumor cells to multiple …

Background: Colorectal cancer (CRC) is a highly widespread malignancy and ranks as the
second most common cause of cancer-related mortality. Objective: Cancer patients …

Colorectal cancer (CRC) continues to be one of the most prevalent and deadliest forms of
cancer worldwide, despite notable advancements in its management. The prognosis for …

Chemotherapy-induced peripheral neuropathy (CIPN) is an important adverse effect of
treatment with oxaliplatin (OXA). We have developed PEGylated nanoliposomal oxaliplatin …