Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut–Liver …

H Jian, Y Liu, X Wang, X Dong, X Zou - International Journal of Molecular …, 2023 - mdpi.com
Appreciation of the importance of Akkermansia muciniphila is growing, and it is becoming
increasingly relevant to identify preventive and/or therapeutic solutions targeting gut–liver …

Gut microbiome, liver immunology, and liver diseases

R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Dysbiosis of human gut microbiome in young-onset colorectal cancer

Y Yang, L Du, D Shi, C Kong, J Liu, G Liu, X Li… - Nature …, 2021 - nature.com
The incidence of sporadic young-onset colorectal cancer (yCRC) is increasing. A significant
knowledge gap exists in the gut microbiota and its diagnostic value for yCRC patients …

[HTML][HTML] Phage therapy: Targeting intestinal bacterial microbiota for the treatment of liver diseases

J Fujiki, B Schnabl - Jhep Reports, 2023 - Elsevier
Phage therapy has been overshadowed by antibiotics for decades. However, it is being
revisited as a powerful approach against antimicrobial-resistant bacteria. As bacterial …

[HTML][HTML] Gut dysbiosis as a driver in alcohol-induced liver injury

B Fairfield, B Schnabl - Jhep Reports, 2021 - Elsevier
Alcohol-related liver disease characterises a broad spectrum of hepatic diseases that result
from heavy alcohol use, and include alcohol-related steatosis, steatohepatitis, fibrosis …

Role of microbiota-derived metabolites in alcoholic and non-alcoholic fatty liver diseases

JW Park, SE Kim, NY Lee, JH Kim, JH Jung… - International Journal of …, 2021 - mdpi.com
Chronic liver disease encompasses diseases that have various causes, such as alcoholic
liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Gut microbiota …

Gut microbiome dysbiosis in alcoholism: consequences for health and recovery

AW Day, CA Kumamoto - Frontiers in cellular and infection …, 2022 - frontiersin.org
Since the mid 1980's, the impact of gastrointestinal (GI) microbiome changes during alcohol
use disorder has been an area of significant interest. This work has resulted in the …

CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease

Y Duan, H Chu, K Brandl, L Jiang, S Zeng… - Nature …, 2021 - nature.com
Complement receptor of immunoglobulin superfamily (CRIg) is expressed on liver
macrophages and directly binds complement component C3b or Gram-positive bacteria to …

Chronic liver diseases and the microbiome—translating our knowledge of gut microbiota to management of chronic liver disease

C Acharya, JS Bajaj - Gastroenterology, 2021 - Elsevier
Chronic liver disease is reaching epidemic proportions with the increasing prevalence of
obesity, nonalcoholic liver disease, and alcohol overuse worldwide. Most patients are not …

Role of gut bacterial and non-bacterial microbiota in alcohol-associated liver disease: Molecular mechanisms, biomarkers, and therapeutic prospective

N Zafari, M Velayati, M Fahim, M Maftouh, G Pourali… - Life Sciences, 2022 - Elsevier
Alcohol-associated liver disease (ALD) comprises a spectrum of liver diseases that include:
steatosis to alcohol-associated hepatitis, cirrhosis, and ultimately hepatocellular carcinoma …