III. IGFs and Their Receptors A. IGF peptides and receptors B. Expression of IGFs and IGF
receptors in the ovary C. Role of IGFs in ovulatory function and steroidogenesis

Interest in characterizing the role of impaired insulin actions in Alzheimer's disease (AD) and
vascular dementia is growing exponentially. This review details what is currently known …

In contrast to conventional theories, a series of provocative epidemiologic findings reported
over the last decade suggest that environmental factors in early life are of substantial …

Insulin-like growth factor 1 receptor (IGF1R)-mediated signaling pathways modulate
important neurophysiological aspects in the central nervous system, including …

Cardiac chamber morphogenesis requires the coordinated growth of both cardiac muscle
and endocardial cell lineages. Paracrine growth factors may modulate the coordinated …

According to the somatomedin model, growth hormone (GH)-dependent hepatic synthesis is
responsible for maintaining circulating insulin-like growth factor (IGF)-I levels. On the other …

Growth factors and cytokines play an important role in the development of central nervous
systems including neurons of the retina. However, the molecular pathways that trigger cell …

Background: To determine whether the following factors are related to birthweight or birth
height, we measured insulin‐like growth factor (IGF)‐I, insulin‐like growth factor binding …

Fetal growth requires the correct balance of nutrients, oxygen, and growth factors operating
under the direction of a genetic plan modified by maternal factors. The classic hormones of …

Organ weight was compared in adult mice with deletion of one (IRS-1−/+) or both (IRS-1−/−)
copies of the insulin receptor substrate-1 (IRS-1) gene and IRS-1+/+ littermates. IRS-1−/+ …