Pesticides are unique environmental contaminants that are specifically introduced into the
environment to control pests, often by killing them. Although pesticide application serves …

Environmental pollutants are recognized as one of the major concerns for public health and
responsible for various forms of neurological disorders. Some of the common sources of …

Three-dimensional (3D) in vitro models have become increasingly popular as systems to
study cell–cell and cell–ECM interactions dependent on the spatial, mechanical, and …

Human pluripotent stem cell (hPSC)-derived neurons provide exciting opportunities for in
vitro modeling of neurological diseases and for advancing drug development and …

Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

Wnt dependency and Lgr5 expression define multiple mammalian epithelial stem cell types.
Under defined growth factor conditions, such adult stem cells (ASCs) grow as 3D organoids …

With the wide adoption of genomic sequencing in children having seizures, an increasing
number of SCN2A genetic variants have been revealed as genetic causes of epilepsy …

Induced pluripotent stem cell (iPSC)-derived neurons are increasingly used to model Autism
Spectrum Disorder (ASD), which is clinically and genetically heterogeneous. To study the …

The brain is the most complex organ of our body. Such a complexity spans from the single-
cell morphology up to the intricate connections that hundreds of thousands of neurons …

The brain is the most complex organ in the body, controlling our highest functions, as well as
regulating myriad processes which incorporate the entire physiological system. The effects …