Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …
Microbiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts
L Ning, YL Zhou, H Sun, Y Zhang, C Shen… - Nature …, 2023 - nature.com
The perturbations of the gut microbiota and metabolites are closely associated with the
progression of inflammatory bowel disease (IBD). However, inconsistent findings across …
progression of inflammatory bowel disease (IBD). However, inconsistent findings across …
Natural and synthetic molecules with potential to enhance biofilm formation and virulence properties in Pseudomonas aeruginosa
Pseudomonas aeruginosa can efficiently adapt to changing environmental conditions due to
its ubiquitous nature, intrinsic/acquired/adaptive resistance mechanisms, high metabolic …
its ubiquitous nature, intrinsic/acquired/adaptive resistance mechanisms, high metabolic …
Inactivation of Pseudomonas aeruginosa biofilms by thymoquinone in combination with nisin
H Chen, PC Ji, YH Qi, SJ Chen, CY Wang… - Frontiers in …, 2023 - frontiersin.org
Pseudomonas aeruginosa is one of the most important foodborne pathogens that can
persist in leafy green vegetables and subsequently produce biofilms. In this study, the …
persist in leafy green vegetables and subsequently produce biofilms. In this study, the …
Ubiquitous purine sensor modulates diverse signal transduction pathways in bacteria
Purines and their derivatives control intracellular energy homeostasis and nucleotide
synthesis, and act as signaling molecules. Here, we combine structural and sequence …
synthesis, and act as signaling molecules. Here, we combine structural and sequence …
Understanding resistance acquisition by Pseudomonas aeruginosa and possible pharmacological approaches in palliating its pathogenesis
Pseudomonas aeruginosa can utilize various virulence factors necessary for host infection
and persistence. These virulence factors include pyocyanin, proteases, exotoxins, 2-heptyl-4 …
and persistence. These virulence factors include pyocyanin, proteases, exotoxins, 2-heptyl-4 …
Lactobacilli, a weapon to counteract pathogens through the inhibition of their virulence factors
A Colautti, E Orecchia, G Comi… - Journal of Bacteriology, 2022 - Am Soc Microbiol
To date, several studies have reported an alarming increase in pathogen resistance to
current antibiotic therapies and treatments. Therefore, the search for effective alternatives to …
current antibiotic therapies and treatments. Therefore, the search for effective alternatives to …
Epidemiology, Molecular Characteristics, and Virulence Factors of Carbapenem-Resistant Pseudomonas aeruginosa Isolated from Patients with Urinary Tract …
Y Park, SH Koo - Infection and Drug Resistance, 2022 - Taylor & Francis
Purpose Pseudomonas aeruginosa is an important pathogen that causes urinary tract
infections. Carbapenems are the drugs of choice for the treatment of P. aeruginosa …
infections. Carbapenems are the drugs of choice for the treatment of P. aeruginosa …
Roles of two-component signal transduction systems in Shigella virulence
M Pasqua, M Coluccia, Y Eguchi, T Okajima, M Grossi… - Biomolecules, 2022 - mdpi.com
Two-component signal transduction systems (TCSs) are widespread types of protein
machinery, typically consisting of a histidine kinase membrane sensor and a cytoplasmic …
machinery, typically consisting of a histidine kinase membrane sensor and a cytoplasmic …