The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells

CT Mierke - Reports on Progress in Physics, 2019 - iopscience.iop.org
The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Melanin presence inhibits melanoma cell spread in mice in a unique mechanical fashion

M Sarna, M Krzykawska-Serda, M Jakubowska… - Scientific reports, 2019 - nature.com
Melanoma is a highly aggressive cancer that exhibits metastasis to various critical organs.
Unlike any other cancer cells, melanoma cells can synthesize melanin in large amounts …

Erythrocytes and their role as health indicator: Using structure in a patient-orientated precision medicine approach

E Pretorius, O Oore-ofe, S Mbotwe, J Bester - Blood reviews, 2016 - Elsevier
The relevance of erythrocyte light microscopy analysis (a well-known haematological
method) is under the spotlight, however there is a place for innovative electron …

[HTML][HTML] Apoptotic human neutrophil peptide-1 anti-tumor activity revealed by cellular biomechanics

D Gaspar, JM Freire, TR Pacheco, JT Barata… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Cancer remains a major cause of morbidity and mortality worldwide. Although progress has
been made regarding chemotherapeutic agents, new therapies that combine increased …

Cancer cell response to extrinsic and intrinsic mechanical cue: opportunities for tumor apoptosis strategies

J Shu, H Deng, Y Zhang, F Wu… - Regenerative Biomaterials, 2024 - academic.oup.com
Increasing studies have revealed the importance of mechanical cues in tumor progression,
invasiveness and drug resistance. During malignant transformation, changes manifest in …

Characterizing cellular mechanical phenotypes with mechano-node-pore sensing

J Kim, S Han, A Lei, M Miyano, J Bloom… - Microsystems & …, 2018 - nature.com
The mechanical properties of cells change with their differentiation, chronological age, and
malignant progression. Consequently, these properties may be useful label-free biomarkers …