Traditional organic synthesis relies heavily on organic solvents for a multitude of tasks,
including dissolving the components and facilitating chemical reactions, because many …

The past decade has seen a substantial increase in successful examples of the combination
of chemo-and biocatalysis for multistep syntheses. This is driven by obvious advantages …

The incorporation of a synthetic, catalytically competent metallocofactor into a protein
scaffold to generate an artificial metalloenzyme (ArM) has been explored since the late …

The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Artificial metalloenzymes (ArMs) result from the incorporation of an abiotic metal cofactor
within a protein scaffold. From the earliest techniques of transition metals adsorbed on silk …

Cascade reactions catalyzed by multienzymatic systems have strongly moved into the focus
of researchers in the field of biocatalysis because of their unique potential for the …

The combination of chemo-and photocatalyses with biocatalysis, which couples the flexible
reactivity of the photo-and chemocatalysts with the highly selective and environmentally …

Platinum-containing drugs (eg, cisplatin) are among the most frequently used
chemotherapeutic agents. Their tremendous success has spurred research and …

Multi-step one-pot chemoenzymatic cascade reactions (mo-CECRs) bridging chemo-and
bio-catalysis can not only accomplish chemical transformations with minimized purification …

Conspectus Artificial metalloenzymes (ArMs) result from anchoring a metal-containing
moiety within a macromolecular scaffold (protein or oligonucleotide). The resulting hybrid …