Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

A Shmatko, N Ghaffari Laleh, M Gerstung, JN Kather - Nature cancer, 2022 - nature.com
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative
information from digital histopathology images. AI is expected to reduce workload for human …

Deep learning in histopathology: the path to the clinic

J Van der Laak, G Litjens, F Ciompi - Nature medicine, 2021 - nature.com
Abstract Machine learning techniques have great potential to improve medical diagnostics,
offering ways to improve accuracy, reproducibility and speed, and to ease workloads for …

Deep neural network models for computational histopathology: A survey

CL Srinidhi, O Ciga, AL Martel - Medical image analysis, 2021 - Elsevier
Histopathological images contain rich phenotypic information that can be used to monitor
underlying mechanisms contributing to disease progression and patient survival outcomes …

Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study

W Bulten, H Pinckaers, H Van Boven, R Vink… - The Lancet …, 2020 - thelancet.com
Summary Background The Gleason score is the strongest correlating predictor of recurrence
for prostate cancer, but has substantial inter-observer variability, limiting its usefulness for …

Measuring domain shift for deep learning in histopathology

K Stacke, G Eilertsen, J Unger… - IEEE journal of …, 2020 - ieeexplore.ieee.org
The high capacity of neural networks allows fitting models to data with high precision, but
makes generalization to unseen data a challenge. If a domain shift exists, ie differences in …

Accelerating histopathology workflows with generative AI-based virtually multiplexed tumour profiling

P Pati, S Karkampouna, F Bonollo… - Nature machine …, 2024 - nature.com
Understanding the spatial heterogeneity of tumours and its links to disease initiation and
progression is a cornerstone of cancer biology. Presently, histopathology workflows heavily …

Recent advances of deep learning for computational histopathology: principles and applications

Y Wu, M Cheng, S Huang, Z Pei, Y Zuo, J Liu, K Yang… - Cancers, 2022 - mdpi.com
Simple Summary The histopathological image is widely considered as the gold standard for
the diagnosis and prognosis of human cancers. Recently, deep learning technology has …

Virtual staining for histology by deep learning

L Latonen, S Koivukoski, U Khan, P Ruusuvuori - Trends in Biotechnology, 2024 - cell.com
In pathology and biomedical research, histology is the cornerstone method for tissue
analysis. Currently, the histological workflow consumes plenty of chemicals, water, and time …

[HTML][HTML] Development and evaluation of deep learning–based segmentation of histologic structures in the kidney cortex with multiple histologic stains

CP Jayapandian, Y Chen, AR Janowczyk, MB Palmer… - Kidney international, 2021 - Elsevier
The application of deep learning for automated segmentation (delineation of boundaries) of
histologic primitives (structures) from whole slide images can facilitate the establishment of …

Generative adversarial networks in digital pathology: a survey on trends and future potential

ME Tschuchnig, GJ Oostingh, M Gadermayr - Patterns, 2020 - cell.com
Image analysis in the field of digital pathology has recently gained increased popularity. The
use of high-quality whole-slide scanners enables the fast acquisition of large amounts of …