[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

Mitochondrial dysfunction and neurological disorders: a narrative review and treatment overview

EE Alshial, MI Abdulghaney, AHS Wadan… - Life Sciences, 2023 - Elsevier
Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

The crosstalk between the gut microbiota and mitochondria during exercise

A Clark, N Mach - Frontiers in physiology, 2017 - frontiersin.org
Many physiological changes occur in response to endurance exercise in order to adapt to
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …

[HTML][HTML] Structure, mechanism, and regulation of mitochondrial DNA transcription initiation

U Basu, AM Bostwick, K Das… - Journal of Biological …, 2020 - Elsevier
Mitochondria are specialized compartments that produce requisite ATP to fuel cellular
functions and serve as centers of metabolite processing, cellular signaling, and apoptosis …

[HTML][HTML] Human mitochondrial DNA: particularities and diseases

M Habbane, J Montoya, T Rhouda, Y Sbaoui… - Biomedicines, 2021 - mdpi.com
Mitochondria are the cell's power site, transforming energy into a form that the cell can
employ for necessary metabolic reactions. These organelles present their own DNA …

Artificial mitochondria transfer: current challenges, advances, and future applications

A Caicedo, PM Aponte, F Cabrera… - Stem cells …, 2017 - Wiley Online Library
The objective of this review is to outline existing artificial mitochondria transfer techniques
and to describe the future steps necessary to develop new therapeutic applications in …

The dimensions of primary mitochondrial disorders

LD Schlieben, H Prokisch - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
The concept of a mitochondrial disorder was initially described in 1962, in a patient with
altered energy metabolism. Over time, mitochondrial energy metabolism has been …

Mitochondrial damage induced by T-2 mycotoxin on human skin—Fibroblast Hs68 cell line

E Janik-Karpinska, M Ceremuga, M Niemcewicz… - Molecules, 2023 - mdpi.com
T-2 toxin is produced by different Fusarium species and belongs to the group of type A
trichothecene mycotoxins. T-2 toxin contaminates various grains, such as wheat, barley …

Current advances in gene therapy of mitochondrial diseases

VO Soldatov, MV Kubekina, MY Skorkina… - Journal of translational …, 2022 - Springer
Mitochondrial diseases (MD) are a heterogeneous group of multisystem disorders involving
metabolic errors. MD are characterized by extremely heterogeneous symptoms, ranging …

Circulating cell-free nucleic acids as epigenetic biomarkers in precision medicine

B Rahat, T Ali, D Sapehia, A Mahajan, J Kaur - Frontiers in genetics, 2020 - frontiersin.org
The circulating cell-free nucleic acids (ccfNAs) are a mixture of single-or double-stranded
nucleic acids, released into the blood plasma/serum by different tissues via apoptosis …