Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Pharmacological tool compounds are now available to define action at the adenosine (ARs),
P2Y and P2X receptors. We present a selection of the most commonly used agents to study …

Abstract Professor Geoffrey Burnstock proposed the concept of purinergic signaling via P1
and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y1, P2Y2, P2Y4, P2Y6 …

Abstract P2Y receptors (P2YRs) are a family of G protein-coupled receptors activated by
extracellular nucleotides. Physiological P2YR agonists include purine and pyrimidine …

Dopamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology
Database Page 1 IUPHAR/BPS Guide to Pharmacology CITE https://doi.org/10.2218/gtopdb/F20/2019.4 …

The purinergic signaling system includes membrane‐bound receptors for extracellular
purines and pyrimidines, and enzymes/transporters that regulate receptor activation by …

UDP and UDP-glucose activate the P2Y14 receptor (P2Y14R) to modulate processes
related to inflammation, diabetes, and asthma. A computational pipeline suggested …

P2Y receptors are expressed in virtually all cells and tissue types and mediate an
astonishing array of biological functions, including platelet aggregation, smooth muscle cell …