The concept of small intestinal bacterial overgrowth (SIBO) arose in the context of
maldigestion and malabsorption among patients with obvious risk factors that permitted the …

Human-microorganism interactions play a key role in human health. However, the
underlying molecular mechanisms remain poorly understood. Small-molecules that offer a …

Background High-fat diet (HFD) is closely associated with the increased prevalence of
inflammatory bowel disease (IBD). Excessive gut microbial metabolite deoxycholic acid …

Abstract Background Bile acids (BAs), synthesized endogenously from cholesterol, play a
central role in metabolic regulation within the enterohepatic circulatory system. Traditionally …

The microbiome is increasingly recognized for its ability to modulate human health.
Colonization with gut symbionts induces Foxp3-expressing regulatory T cells (Tregs) and …

Adoptive cell therapies, like tumor-infiltrating lymphocytes or chimeric antigen receptor T
cells, have become an important immunotherapeutic approach against cancer. One of the …

Inflammatory bowel disease (IBD) is an autoimmune disease characterized by non-
infectious, chronic, and recurrent inflammation in the intestine, with unclear pathogenesis …

Human-microorganism interactions play a key role in human health. However, the
underlying molecular mechanisms remain poorly understood. Small-molecules that offer a …

Fecal microbiota transplantation (FMT) has emerged as the most effective therapy for
recurrent Clostridioides difficileinfections (rCDI); yet the role of immune cells in the response …